Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8685698 | 0.85 | CA2 (0.55) | SMN1; SMN2ALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL20314711 | 0.82 | ALDH1A1 (0.49) | XDHSMN1; SMN2ALDH1A1GAALMNA | |
| SCHEMBL27939594 | 0.81 | ALDH1A1 (0.48) | XDHSMN1; SMN2ALDH1A1GAALMNA | |
| SCHEMBL2617468 | 0.81 | ABCB1 (0.54) | SMN1; SMN2ALDH1A1LMNAKDM4EMEN1 | |
| SCHEMBL3459059 | 0.78 | PDE4B (0.47) | SMN1; SMN2LMNAMEN1MAPTKMT2A | |
| SCHEMBL580059 | 0.76 | NPC1 (0.54) | XDHSMN1; SMN2ALDH1A1GAALMNA | |
| SCHEMBL7791111 | 0.76 | ALDH1A1 (0.52) | XDHSMN1; SMN2ALDH1A1GAALMNA | |
| SCHEMBL3457950 | 0.76 | MEN1 (0.45) | MEN1HTTKMT2A | |
| SCHEMBL24947871 | 0.75 | ALDH1A1 (0.58) | XDHSMN1; SMN2ALDH1A1GAALMNA | |
| SCHEMBL17913604 | 0.75 | CA5A (0.39) | SMN1; SMN2ALDH1A1GAALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010010435-A2 | FUSED OXAZOLE AND THIAZOLE DERIVATIVES AS TRPMS MODULATORS | GLENMARK PHARMACEUTICAL S.A. (CH) | 2010-01-28 | — | — | WO | disclosed |