Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ALDH2 | P05091 | 5/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10140121 | 0.86 | POLB (0.52) | POLBHPGDALDH1A1ALDH2P2RX7 | |
| SCHEMBL6888143 | 0.86 | POLB (0.46) | POLBHPGDALDH1A1P2RX7JAK2 | |
| SCHEMBL6030405 | 0.85 | P2RX7 (0.43) | POLBHPGDALDH1A1P2RX7TSHR | |
| SCHEMBL3457151 | 0.84 | P2RX7 (0.41) | POLBHPGDP2RX7TSHR | |
| SCHEMBL15788682 | 0.84 | POLB (0.50) | POLBHPGDALDH1A1ALDH2P2RX7 | |
| SCHEMBL15286566 | 0.83 | KMT2A (0.61) | POLBALDH1A1P2RX7 | |
| SCHEMBL29356683 | 0.83 | KMT2A (0.61) | POLBALDH1A1P2RX7 | |
| SCHEMBL21950 | 0.83 | KMT2A (0.61) | POLBALDH1A1P2RX7 | |
| SCHEMBL18197098 | 0.79 | MEN1 (0.48) | POLBHPGDALDH1A1ALDH2P2RX7 | |
| SCHEMBL6029625 | 0.78 | KMT2A (0.43) | POLBHPGDALDH1A1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1484970-B1 | BENZAMIDES AND COMPOSITIONS COMPRISING BENZAMIDES FOR USE AS FUNGICIDES | DU PONT (US) | 2013-06-26 | — | — | EP | claimed |
| EP-2260704-B1 | Fungicidal compositions comprising a benzamide and cymoxanil | DU PONT (US) | 2013-10-16 | — | — | EP | disclosed |
| EP-1484970-B1 | BENZAMIDES AND COMPOSITIONS COMPRISING BENZAMIDES FOR USE AS FUNGICIDES | DU PONT (US) | 2013-06-26 | — | — | EP | disclosed |
| EP-2260705-A2 | Fungicidal compositions comprising a benzamide and a michondrial respiration inhibitor | E. I. du Pont de Nemours and Company (US) | 2010-12-15 | — | — | EP | disclosed |
| EP-2260703-A2 | Fungicidal compositions comprising a benzamide and fosetyl-aluminium | E. I. du Pont de Nemours and Company (US) | 2010-12-15 | — | — | EP | disclosed |
| EP-2260704-A2 | Fungicidal compositions comprising a benzamide and cymoxanil | E. I. du Pont de Nemours and Company (US) | 2010-12-15 | — | — | EP | disclosed |
| EP-2258190-A2 | Fungicidal compositions comprising a benzamide and a phthalimide | E. I. du Pont de Nemours and Company (US) | 2010-12-08 | — | — | EP | disclosed |
| EP-1056723-B1 | 2-PYRIDYLMETHYLAMINE DERIVATIVES USEFUL AS FUNGICIDES | BAYER CROPSCIENCE LTD (GB) | 2007-11-28 | — | — | EP | disclosed |
| US-20050164999-A1 | Benzamides and compositions benzamides for use as fungicizide | E. I. DU PONT DE NEMOURS AND COMPANY | 2005-07-28 | — | — | US | disclosed |
| EP-1484970-A2 | BENZAMIDES AND COMPOSITIONS COMPRISING BENZAMIDES FOR USE AS FUNGICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2004-12-15 | — | — | EP | disclosed |
| US-6828441-B2 | Agriculture | AVENTIS CROPSCIENCE UK LIMITED (GB) | 2004-12-07 | — | — | US | disclosed |
| WO-2003079788-A2 | BENZAMIDES AND COMPOSITIONS BENZAMIDES FOR USE AS FUNGIZIDE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-10-02 | — | — | WO | disclosed |
| US-20030171410-A1 | 2-pyridylmethylamine derivatives useful as fungicides | AVENTIS CROPSCIENCE UK LIMITED | 2003-09-11 | — | — | US | disclosed |
| US-6503933-B1 | Combating phytopathogenic fungi | AVENTIS CROPSCIENCE UK LIMITED (GB) | 2003-01-07 | — | — | US | disclosed |
| EP-1056723-A1 | 2-PYRIDYLMETHYLAMINE DERIVATIVES USEFUL AS FUNGICIDES | Aventis CropScience UK Limited (GB) | 2000-12-06 | — | — | EP | disclosed |
| WO-1999042447-A1 | 2-PYRIDYLMETHYLAMINE DERIVATIVES USEFUL AS FUNGICIDES | AVENTIS CROPSCIENCE UK LIMITED (GB) | 1999-08-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030171410-A1 | 2-pyridylmethylamine derivatives useful as fungicides | PNPO, ME1, CYP2S1 | POLB 4038/4885HPGD 2280/4885ALDH1A1 1091/4885 |
| US-20050164999-A1 | Benzamides and compositions benzamides for use as fungicizide | CYC1, ME3, ME2 | POLB 1571/4885HPGD 2181/4885ALDH1A1 2079/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.