Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3456777 | 0.99 | RAB9A (0.33) | NPC1GAANFKB1RAB9ANFKB2 | |
| SCHEMBL27567063 | 0.99 | RAB9A (0.33) | NPC1GAANFKB1RAB9ANFKB2 | |
| SCHEMBL27627490 | 0.96 | NPC1 (0.34) | NPC1GAANFKB1RAB9ANFKB2 | |
| SCHEMBL5502528 | 0.95 | NPC1 (0.33) | NPC1GAANFKB1RAB9ANFKB2 | |
| SCHEMBL3457852 | 0.90 | MMP2 (0.34) | PDK2 | |
| SCHEMBL516329 | 0.89 | NPC1 (0.33) | NPC1GAANFKB1RAB9ANFKB2 | |
| SCHEMBL1572292 | 0.88 | RAB9A (0.36) | NPC1GAANFKB1RAB9ANFKB2 | |
| SCHEMBL31228771 | 0.88 | RAB9A (0.36) | NPC1GAANFKB1RAB9ANFKB2 | |
| SCHEMBL4532916 | 0.87 | LMNA (0.36) | NPC1GAANFKB1RAB9ANFKB2 | |
| SCHEMBL13708994 | 0.87 | LMNA (0.36) | NPC1GAANFKB1RAB9ANFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1425168-A4 | LIGHT-EMITTING ORGANIC OLIGOMER COMPOSITIONS | UNIV ROCHESTER (US) | 2007-01-03 | — | — | EP | disclosed |
| US-7057009-B2 | Crosslinking polyfluorene; molecular orientation | UNIVERSITY OF ROCHESTER (US) | 2006-06-06 | — | — | US | disclosed |
| EP-1425168-A2 | LIGHT-EMITTING ORGANIC OLIGOMER COMPOSITIONS | University of Rochester (US) | 2004-06-09 | — | — | EP | disclosed |
| US-20030039838-A1 | Light-emitting organic oligomer compositions | UNIVERSITY OF ROCHESTER | 2003-02-27 | — | — | US | disclosed |
| WO-2003008475-A2 | LIGHT-EMITTING ORGANIC OLIGOMER COMPOSITIONS | UNIVERSITY OF ROCHESTER (US) | 2003-01-30 | — | — | WO | disclosed |