SCHEMBL3456777

SCHEMBL3456777

CCCCCCCCC1(CCCCCCCC)c2cc(Br)ccc2-c2ccc([Si](C)(C)C)cc21

nearest known ligand 0.33

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.33
NPC1 O15118 1/20 0.33
GAA P10253 1/20 0.33
NFKB1 P19838 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
PDK2 Q15119 2/20 0.32
MAPT P10636 1/20 0.32
MMP2 P08253 2/20 0.30
MMP9 P14780 2/20 0.30
MMP8 P22894 2/20 0.30
MMP13 P45452 2/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C19 P33261 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27567063 1.00 RAB9A (0.33) RAB9ANPC1GAANFKB1NFKB2
SCHEMBL5498381 0.99 NPC1 (0.33) RAB9ANPC1GAANFKB1NFKB2
SCHEMBL27627490 0.94 NPC1 (0.34) RAB9ANPC1GAANFKB1NFKB2
SCHEMBL5502528 0.94 NPC1 (0.33) RAB9ANPC1GAANFKB1NFKB2
SCHEMBL3457852 0.92 MMP2 (0.34) PDK2MMP2MMP9MMP8MMP13
SCHEMBL516329 0.90 NPC1 (0.33) RAB9ANPC1GAANFKB1NFKB2
SCHEMBL13708994 0.89 LMNA (0.36) RAB9ANPC1GAANFKB1NFKB2
SCHEMBL197894 0.89 LMNA (0.36) RAB9ANPC1GAANFKB1NFKB2
SCHEMBL196456 0.89 LMNA (0.36) RAB9ANPC1GAANFKB1NFKB2
SCHEMBL197316 0.89 LMNA (0.36) RAB9ANPC1GAANFKB1NFKB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2264123-B1 PROCESS FOR THE PREPARATION OF SOLUTION-PROCESSABLE PHOSPHORESCENT MATERIALS CAMBRIDGE ENTPR LTD (GB) 2016-12-28 EP disclosed
EP-1501907-B1 SOLUTION-PROCESSABLE PHOSPHORESCENT MATERIALS CAMBRIDGE ENTPR LTD (GB) 2016-07-27 EP disclosed
CN-101230264-B The phosphor material of solution processable CAMBRIDGE ENTPR LTD. (GB) 2015-08-12 CN disclosed
US-9023978-B2 Solution-processable phosphorescent materials CAMBRIDGE ENTERPRISE LTD. (GB) 2015-05-05 US disclosed
EP-2264123-A2 Solution-processable phosphorescent materials Cambridge Display Technology Limited (GB) 2010-12-22 EP disclosed
US-7119360-B2 Light-emitting polymers and electronic devices using such polymers MAX-PLANK-SOCIETY (DE) 2006-10-10 US disclosed
US-7115899-B2 Light-emitting copolymers and electronic devices using such copolymers E. I. DU PONT DE NEMOURS AND COMPANY (US) 2006-10-03 US disclosed
US-20060192198-A1 LIGHT-EMITTING COPOLYMERS AND ELECTRONIC DEVICES USING SUCH COPOLYMERS LG CHEM, LTD. (KR) 2006-08-31 US disclosed
US-20060063026-A1 Solution-processable phosphorescent materials CAMBRIDGE ENTERPRISE LTD (GB) 2006-03-23 US disclosed
WO-2005042176-A9 LIGHT-EMITTING COPOLYMERS AND ELECTRONIC DEVICES USING SUCH COPOLYMERS DU PONT (US) 2006-01-05 WO disclosed
WO-2005042176-A1 LIGHT-EMITTING COPOLYMERS AND ELECTRONIC DEVICES USING SUCH COPOLYMERS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2005-05-12 WO disclosed
WO-2005042614-A1 LIGHT-EMITTING POLYMERS AND ELECTRONIC DEVICES USING SUCH POLYMERS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2005-05-12 WO disclosed
US-20050092982-A1 Light-emitting polymers and electronic devices using such polymers MAX PLANCK SOCIETY (DE) 2005-05-05 US disclosed
EP-1501907-A2 SOLUTION-PROCESSABLE PHOSPHORESCENT MATERIALS CAMBRIDGE UNIVERSITY TECHNICAL SERVICES LIMITED (GB) 2005-02-02 EP disclosed
WO-2003091355-A2 SOLUTION-PROCESSABLE PHOSPHORESCENT MATERIALS CAMBRIDGE UNIVERSITY TECHNICAL SERVICES LIMITED (GB) 2003-11-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050092982-A1 Light-emitting polymers and electronic devices using such polymers PPOX, PDK4, PIN4 RAB9A 4128/4885NPC1 4763/4885GAA 2230/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.