Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10890850 | 0.84 | CHEK1 (0.38) | ADRB1LMNACYP2D6MEN1CYP1A2 | |
| SCHEMBL9462184 | 0.84 | ADRB1 (0.37) | ADRB1LMNACYP2D6MEN1CYP1A2 | |
| SCHEMBL10864562 | 0.80 | ADRB1 (0.36) | ADRB1LMNACYP2D6MEN1CYP1A2 | |
| SCHEMBL11254105 | 0.79 | PARP15 (0.38) | ADRB1LMNACYP2D6MEN1CYP1A2 | |
| SCHEMBL29982657 | 0.79 | NR3C1 (0.38) | ADRB1CYP2D6KMT2AADRB2HTR2C | |
| SCHEMBL13953857 | 0.76 | LMNA (0.57) | ADRB1LMNACYP2D6MEN1CYP1A2 | |
| SCHEMBL28715980 | 0.75 | THRB (0.41) | CYP2D6MEN1CYP1A2CYP2C9KMT2A | |
| SCHEMBL21505015 | 0.75 | ADRB1 (0.49) | ADRB1LMNACYP2D6MEN1CYP1A2 | |
| SCHEMBL10863679 | 0.75 | GABRA1 (0.37) | ADRB1LMNACYP2D6MEN1CYP1A2 | |
| SCHEMBL27554627 | 0.75 | ADRB1 (0.50) | ADRB1LMNACYP2D6MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010029566-A2 | PROCESS FOR PREPARATION OF PHENOXYPROPANOL AMINES | INDOCO REMEDIES LIMITED (IN) | 2010-03-18 | — | — | WO | disclosed |
| EP-0168921-A2 | Chemical compounds | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1986-01-22 | — | — | EP | disclosed |