Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | ICMT | O60725 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GPX4 | P36969 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15352674 | 1.00 | NPC1 (0.50) | NPC1RAB9APAX8JAK2KCNH2 | |
| SCHEMBL16414652 | 1.00 | NPC1 (0.50) | NPC1RAB9APAX8JAK2KCNH2 | |
| SCHEMBL7651316 | 1.00 | NPC1 (0.50) | NPC1RAB9APAX8JAK2KCNH2 | |
| SCHEMBL16415140 | 1.00 | NPC1 (0.50) | NPC1RAB9APAX8JAK2KCNH2 | |
| SCHEMBL7914609 | 1.00 | NPC1 (0.50) | NPC1RAB9APAX8JAK2KCNH2 | |
| SCHEMBL707049 | 1.00 | NPC1 (0.50) | NPC1RAB9APAX8JAK2KCNH2 | |
| SCHEMBL704306 | 0.98 | NPC1 (0.47) | NPC1RAB9APAX8JAK2KCNH2 | |
| SCHEMBL489807 | 0.93 | TDP1 (0.44) | NPC1RAB9APAX8JAK2KCNH2 | |
| SCHEMBL709443 | 0.85 | TP53 (0.43) | NPC1RAB9APAX8JAK2TP53 | |
| SCHEMBL11825722 | 0.82 | NPC1 (0.46) | NPC1RAB9APAX8JAK2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841433-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE | SUMITOMO CHEMICAL CO (JP) | 2017-06-21 | — | — | EP | disclosed |
| US-9380782-B2 | Tetrazolinone compounds and its use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-07-05 | — | — | US | disclosed |
| EP-2841433-A1 | TETRAZOLINONE COMPOUNDS AND ITS USE | Sumitomo Chemical Company Limited (JP) | 2015-03-04 | — | — | EP | disclosed |
| US-20150031733-A1 | TETRAZOLINONE COMPOUNDS AND ITS USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-01-29 | — | — | US | disclosed |
| WO-2013162077-A1 | TETRAZOLINONE COMPOUNDS AND ITS USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-10-31 | — | — | WO | disclosed |
| EP-2169010-A2 | Method of producing organic pigment fine-particles, organic pigment fine-particles obtained thereby, liquid dispersion thereof, and composition thereof | FUJIFILM Corporation (JP) | 2010-03-31 | — | — | EP | disclosed |
| US-7071211-B2 | Small organic molecules that increase the activity of gelatinase a in ocular cells | BAUSCH & LOMB INC. (US) | 2006-07-04 | — | — | US | disclosed |
| US-20060121090-A1 | Ocular compositions that increases the activity of gelatinase a in ocular cells | BAUSCH & LOMB INCORPORATED | 2006-06-08 | — | — | US | disclosed |
| EP-1542687-A1 | SMALL ORGANIC MOLECULES THAT INCREASE THE ACTIVITY OF GELATINASE A IN OCULAR CELLS | BAUSCH & LOMB INCORPORATED (US) | 2005-06-22 | — | — | EP | disclosed |
| WO-2004028538-A1 | SMALL ORGANIC MOLECULES THAT INCREASE THE ACTIVITY OF GELATINASE A IN OCULAR CELLS | BAUSCH & LOMB INCORPORATED (US) | 2004-04-08 | — | — | WO | disclosed |
| US-20040068017-A1 | Small organic molecules that increase the activity of Gelatinase A in ocular cells | BAUSCH & LOMB INCORPORATED | 2004-04-08 | — | — | US | disclosed |
| EP-0137271-B1 | METHOD OF IMPROVING THE LIGHT RESISTANCE OF A DYE IMAGE | KONICA CORPORATION (JP) | 1987-11-04 | — | — | EP | disclosed |
| US-4540653-A | METAL COMPLEX, ANILINO COUPLER | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1985-09-10 | — | — | US | disclosed |
| EP-0137271-A2 | Method of improving the light resistance of a dye image | KONICA CORPORATION (JP) | 1985-04-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060121090-A1 | Ocular compositions that increases the activity of gelatinase a in ocular cells | MMP3, MMP13, MMP1 | NPC1 951/4885RAB9A 337/4885PAX8 527/4885 |
| US-20040068017-A1 | Small organic molecules that increase the activity of Gelatinase A in ocular cells | MMP1, MMP3, MMP10 | NPC1 1146/4885RAB9A 721/4885PAX8 967/4885 |
| US-20150031733-A1 | TETRAZOLINONE COMPOUNDS AND ITS USE | CBR3, CYP51A1, CYP8B1 | NPC1 2859/4885RAB9A 515/4885PAX8 4742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.