SCHEMBL345860

SCHEMBL345860

CC1(C)OC[C@@H]([C@@H](O)C(=O)O)O1

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HCRTR1 O43613 4/20 0.35
HCRTR2 O43614 4/20 0.35
TMEM97 Q5BJF2 1/20 0.31
SIGMAR1 Q99720 1/20 0.31
CA2 P00918 2/20 0.31
IDUA P35475 1/20 0.31
GUSB P08236 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8169843 1.00 HCRTR1 (0.35) HCRTR1HCRTR2TMEM97SIGMAR1CA2
SCHEMBL18302566 1.00 HCRTR1 (0.35) HCRTR1HCRTR2TMEM97SIGMAR1CA2
SCHEMBL346996 1.00 HCRTR1 (0.35) HCRTR1HCRTR2TMEM97SIGMAR1CA2
SCHEMBL346997 1.00 HCRTR1 (0.35) HCRTR1HCRTR2TMEM97SIGMAR1CA2
SCHEMBL18682065 1.00 HCRTR1 (0.35) HCRTR1HCRTR2TMEM97SIGMAR1CA2
SCHEMBL25387433 1.00 HCRTR1 (0.35) HCRTR1HCRTR2TMEM97SIGMAR1CA2
SCHEMBL9332338 0.98 HCRTR1 (0.35) HCRTR1HCRTR2TMEM97SIGMAR1CA2
SCHEMBL5042482 0.98 HCRTR1 (0.35) HCRTR1HCRTR2TMEM97SIGMAR1CA2
Water SCHEMBL10648449 0.96 HCRTR1 (0.34) HCRTR1HCRTR2TMEM97SIGMAR1
SCHEMBL14793014 0.86 HCRTR1 (0.33) HCRTR1HCRTR2CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10633390-B2 Process for the preparation of [(1S,2R)-3-[[(4-aminophenyl)sulfonyl] (2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-carbamic acid (3R,3AS,6AR)hexahydro furo [2,3-B]furan-3-YL ester and its amorphous form MSN LABORATORIES PRIVATE LIMITED (IN) 2020-04-28 US claimed
US-20180370982-A1 PROCESS FOR THE PREPARATION OF [(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL] (2-METHYLPROPYL)AMINO]-2-HYDROXY-1-(PHENYLMETHYL)PROPYL]-CARBAMIC ACID (3R,3AS,6AR)HEXAHYDRO FURO[2,3-B]FURAN-3-YL ESTER AND ITS AMORPHOUS FORM MSN LABORATORIES PRIVATE LIMITED (IN) 2018-12-27 US claimed
EP-3313847-A1 PROCESS FOR THE PREPARATION OF [(1 S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](2-METHYLPROPYL)AMINO]-2-HYDROXY-1 -(PHENYLMETHYL)PROPYL]-CARBAMIC ACID (3R,3AS,6AR)HEXAHYDRO FURO[2,3-B]FURAN-3-YL ESTER AND ITS AMORPHOUS FORM MSN Laboratories Private Limited (IN) 2018-05-02 EP claimed
WO-2016207907-A1 PROCESS FOR THE PREPARATION OF [(1 S,2R)-3-[[(4-AMINOPHENYL)SULFONYL] (2-METHYLPROPYL)AMINO]-2-HYDROXY-1 -(PHENYLMETHYL)PROPYL]-CARBAMIC ACID (3R,3AS,6AR)HEXAHYDRO FURO[2,3-B]FURAN-3-YL ESTER AND ITS AMORPHOUS FORM MSN LABORATORIES PRIVATE LIMITED (IN) 2016-12-29 WO claimed
US-7361775-B2 Process for the preparation of (S)-glyceraldehyde acetonide DSM IP ASSETS B.V. (NL) 2008-04-22 US claimed
EP-1673364-B1 PROCESS FOR THE PREPARATION OF (S)-GLYCERALDEHYDE ACETONIDE DSM IP ASSETS BV (NL) 2007-08-22 EP claimed
US-20070073068-A1 Process for the preparation of (s)-glyceraldehyde acetonide DSM IP ASSETS B.V. (NL) 2007-03-29 US claimed
CN-1863787-A Process for the preparation of -glyceraldehyde acetonide DSM IP ASSETS BV (NL) 2006-11-15 CN claimed
EP-1673364-A1 PROCESS FOR THE PREPARATION OF (S)-GLYCERALDEHYDE ACETONIDE DSM IP Assets B.V. (NL) 2006-06-28 EP claimed
WO-2005037819-A1 PROCESS FOR THE PREPARATION OF (S)-GLYCERALDEHYDE ACETONIDE DSM IP ASSETS B.V. (NL) 2005-04-28 WO claimed
EP-0111326-B1 PROCESS FOR THE MANUFACTURE OF CHIRAL AZETIDINONES F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1989-01-11 EP claimed
EP-0143973-B1 METHOD OF PRODUCING (S)-GLYCERALDEHYDE ACETONIDE Takeda Chemical Industries, Ltd. (JP) 1988-03-02 EP claimed
CN-85101931-A The preparation method of symmetry (S)-Glycerose acetonide 1987-01-24 CN claimed
US-4567282-A Method of producing (S)-glyceraldehyde acetonide TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1986-01-28 US claimed
EP-0143973-A1 Method of producing (S)-Glyceraldehyde Acetonide Takeda Chemical Industries, Ltd. (JP) 1985-06-12 EP claimed
JP-60094977-A None JP disclosed
US-11279735-B2 Cyclic peptide antibiotics GENENTECH, INC. (US) 2022-03-22 US disclosed
US-4567282-A Method of producing (S)-glyceraldehyde acetonide TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1986-01-28 US disclosed
EP-0143973-A1 Method of producing (S)-Glyceraldehyde Acetonide Takeda Chemical Industries, Ltd. (JP) 1985-06-12 EP disclosed
JP-S6094977-A PRODUCTION OF (S)-GLYCERALDEHYDE ACETONIDE TAKEDA CHEM IND LTD 1985-05-28 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10633390-B2 Process for the preparation of [(1S,2R)-3-[[(4-aminophenyl)sulfonyl] (2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-carbamic acid (3R,3AS,6AR)hexahydro furo [2,3-B]furan-3-YL ester and its amorphous form FFAR1, CYP2S1, CYP1B1 HCRTR1 1258/4885HCRTR2 2134/4885TMEM97 2110/4885
US-20070073068-A1 Process for the preparation of (s)-glyceraldehyde acetonide AKR1C3, AK1, GAPDH HCRTR1 1773/4885HCRTR2 2660/4885TMEM97 4333/4885
US-20180370982-A1 PROCESS FOR THE PREPARATION OF [(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL] (2-METHYLPROPYL)AMINO]-2-HYDROXY-1-(PHENYLMETHYL)PROPYL]-CARBAMIC ACID (3R,3AS,6AR)HEXAHYDRO FURO[2,3-B]FURAN-3-YL ESTER AND ITS AMORPHOUS FORM FFAR1, CYP2S1, FFAR3 HCRTR1 1277/4885HCRTR2 2123/4885TMEM97 2137/4885
US-11279735-B2 Cyclic peptide antibiotics NPPA, LNPEP, CLPP HCRTR1 4581/4885HCRTR2 4650/4885TMEM97 2176/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.