SCHEMBL3482393

SCHEMBL3482393

N#CCCN1C(=O)C=CC1=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 9/20 0.54
FAAH O00519 5/20 0.54
NPSR1 Q6W5P4 3/20 0.52
ALDH1A1 P00352 2/20 0.52
LMNA P02545 2/20 0.52
MAPT P10636 2/20 0.52
HSP90AA1 P07900 1/20 0.52
TLR9 Q9NR96 1/20 0.52
TP53 P04637 1/20 0.52
PKM P14618 1/20 0.52
HPGD P15428 1/20 0.52
XBP1 P17861 1/20 0.52
MAPK1 P28482 1/20 0.52
HTT P42858 1/20 0.52
RECQL P46063 1/20 0.52
RAB9A P51151 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
GPR35 Q9HC97 1/20 0.52
GPR55 Q9Y2T6 1/20 0.52
PTGS1 P23219 7/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34594 0.78 MGLL (0.56) MGLLFAAHNPSR1ALDH1A1LMNA
SCHEMBL14587456 0.76 MGLL (0.54) MGLLFAAHNPSR1ALDH1A1LMNA
SCHEMBL14678413 0.76 MGLL (0.77) MGLLFAAHNPSR1ALDH1A1LMNA
SCHEMBL145737 0.76 MGLL (0.77) MGLLFAAHNPSR1ALDH1A1LMNA
SCHEMBL10699322 0.75 MGLL (0.46) MGLLFAAHNPSR1ALDH1A1LMNA
SCHEMBL366266 0.74 MGLL (0.65) MGLLFAAHNPSR1ALDH1A1LMNA
SCHEMBL17070888 0.73 MGLL (0.50) MGLLFAAHNPSR1ALDH1A1LMNA
SCHEMBL19514746 0.73 MGLL (0.70) MGLLFAAHNPSR1ALDH1A1LMNA
SCHEMBL5810929 0.71 ALDH1A1 (0.42) MGLLFAAHNPSR1ALDH1A1PKM
SCHEMBL28949199 0.71 MAOA (0.37) NPSR1ALDH1A1MAPTMAPK1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5115061-A N-propionitrile maleimides, preparation process and polymers thereof GENERAL ELECTRIC COMPANY (US) 1992-05-19 US claimed
CN-115536776-B Resin for photoresist, preparation method thereof and photoresist prepared from resin 瑞红(苏州)电子化学品股份有限公司 2023-08-29 CN disclosed
CN-115536776-A Resin for photoresist, preparation method thereof and photoresist prepared from resin 瑞红(苏州)电子化学品股份有限公司 2022-12-30 CN disclosed
US-8420764-B2 Compound having silsesquioxane skeleton and its polymer JNC CORPORATION (JP) 2013-04-16 US disclosed
US-8236917-B2 Compound having silsesquioxane skeleton and its polymer JNC CORPORATION (JP) 2012-08-07 US disclosed
US-20120178894-A1 COMPOUND HAVING SILSESQUIOXANE SKELETON AND ITS POLYMER INAGAKI JYUN-ICHI (JP) 2012-07-12 US disclosed
US-20100240855-A1 Compound having silsesquioxane skeleton and its polymer JNC CORPORATION (JP) 2010-09-23 US disclosed
US-7705105-B2 A cyclic polymer of silsesquioxane skeleton with side chains formed byhydrosilation of an unsaturated end group containing an active polymerfunctional group; polyimidesiloxane copolymers; polyestersiloxane copolymers; high molecular weight; thin films; strength; heat resistance;waterproofing; CHISSO PETROCHEMICAL CORPORATION (JP) 2010-04-27 US disclosed
US-20070190344-A1 Verification of translation JNC CORPORATION (JP) 2007-08-16 US disclosed
US-20050009982-A1 Compound having silsesquioxane skeleton and its polymer CHISSO CORPORATION (JP) 2005-01-13 US disclosed
US-5115061-A N-propionitrile maleimides, preparation process and polymers thereof GENERAL ELECTRIC COMPANY (US) 1992-05-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050009982-A1 Compound having silsesquioxane skeleton and its polymer C1S, H1-4, H1-0 MGLL 4700/4885FAAH 4471/4885NPSR1 1025/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.