Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3459697 | 0.93 | HRH3 (0.45) | KMT2AHSD17B10LTA4HPTGS2KDM4E | |
| SCHEMBL3459880 | 0.89 | FLT3 (0.44) | KMT2AHSD17B10LTA4HPTGS2KDM4E | |
| SCHEMBL3461224 | 0.88 | HSD17B10 (0.49) | HSD17B10KDM4EL3MBTL1PARP1ALDH1A1 | |
| SCHEMBL3461678 | 0.85 | FLT3 (0.49) | HSD17B10LTA4HPOLBKDM4EPARP1 | |
| SCHEMBL3461960 | 0.85 | HTT (0.53) | KMT2ALTA4HPTGS2POLBMEN1 | |
| SCHEMBL3462580 | 0.84 | HTT (0.51) | KMT2ALTA4HPTGS2POLBKDM4E | |
| SCHEMBL3460234 | 0.84 | LTA4H (0.49) | HSD17B10LTA4HPOLBKDM4EHRH3 | |
| SCHEMBL3462893 | 0.84 | POLB (0.48) | KMT2ALTA4HPOLBKDM4EALDH1A1 | |
| SCHEMBL13463747 | 0.83 | FLT3 (0.40) | KMT2AHSD17B10LTA4HPTGS2KDM4E | |
| SCHEMBL3462494 | 0.82 | KMT2A (0.38) | KMT2AHSD17B10POLBKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2694057-B1 | LIPOXYGENASE INHIBITORS | STANFORD RES INST INT (US) | 2019-06-05 | — | — | EP | claimed |
| EP-2694057-B1 | LIPOXYGENASE INHIBITORS | STANFORD RES INST INT (US) | 2019-06-05 | — | — | EP | disclosed |
| EP-2326327-B1 | ANALOGS OF INDOLE-3-CARBINOL AND THEIR USE AS AGENTS AGAINST INFECTION | STANFORD RES INST INT (US) | 2016-03-23 | — | — | EP | disclosed |
| EP-2326327-B1 | ANALOGS OF INDOLE-3-CARBINOL AND THEIR USE AS AGENTS AGAINST INFECTION | STANFORD RES INST INT (US) | 2016-03-23 | — | — | EP | disclosed |
| EP-2694057-A1 | LIPOXYGENASE INHIBITORS | SRI International (US) | 2014-02-12 | — | — | EP | disclosed |
| US-20130345214-A1 | Lipoxygenase Inhibitors | SRI INTERNATIONAL, INC. (US) | 2013-12-26 | — | — | US | disclosed |
| US-8399502-B2 | Analogs of indole-3-carbinol and their use as agents against infection | SRI INTERNATIONAL (US) | 2013-03-19 | — | — | US | disclosed |
| US-8399502-B2 | Analogs of indole-3-carbinol and their use as agents against infection | SRI INTERNATIONAL (US) | 2013-03-19 | — | — | US | disclosed |
| US-8399502-B2 | Analogs of indole-3-carbinol and their use as agents against infection | SRI INTERNATIONAL (US) | 2013-03-19 | — | — | US | disclosed |
| US-20120283240-A1 | Analogs of Indole-3-Carbinol and Their Use as Agents Against Infection | SRI INTERNATIONAL | 2012-11-08 | — | — | US | disclosed |
| US-20120283240-A1 | Analogs of Indole-3-Carbinol and Their Use as Agents Against Infection | SRI INTERNATIONAL | 2012-11-08 | — | — | US | disclosed |
| US-20120283240-A1 | Analogs of Indole-3-Carbinol and Their Use as Agents Against Infection | SRI INTERNATIONAL | 2012-11-08 | — | — | US | disclosed |
| WO-2012135133-A1 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2012-10-04 | — | — | WO | disclosed |
| US-8278341-B2 | Analogs of indole-3-carbinol and their use as agents against infection | SRI INTERNATIONAL (US) | 2012-10-02 | — | — | US | disclosed |
| US-8278341-B2 | Analogs of indole-3-carbinol and their use as agents against infection | SRI INTERNATIONAL (US) | 2012-10-02 | — | — | US | disclosed |
| US-8278341-B2 | Analogs of indole-3-carbinol and their use as agents against infection | SRI INTERNATIONAL (US) | 2012-10-02 | — | — | US | disclosed |
| WO-2010033198-A2 | ANALOGS OF INDOLE-3-CARBINOL AND THEIR USE AS AGENTS AGAINST INFECTION | SRI INTERNATIONAL (US) | 2010-03-25 | — | — | WO | disclosed |
| US-20100069355-A1 | Analogs of Indole-3-Carbinol and Their Use as Agents Against Infection | UNITED STATES GOVERNMENT; DEFENSE THREAT REDUCTION AGENCY | 2010-03-18 | — | — | US | disclosed |
| US-20100069355-A1 | Analogs of Indole-3-Carbinol and Their Use as Agents Against Infection | UNITED STATES GOVERNMENT; DEFENSE THREAT REDUCTION AGENCY | 2010-03-18 | — | — | US | disclosed |
| US-20100069355-A1 | Analogs of Indole-3-Carbinol and Their Use as Agents Against Infection | UNITED STATES GOVERNMENT; DEFENSE THREAT REDUCTION AGENCY | 2010-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120283240-A1 | Analogs of Indole-3-Carbinol and Their Use as Agents Against Infection | IDO1, IDO2, TDO2 | KMT2A 2912/4885HSD17B10 1780/4885LTA4H 1347/4885 |
| US-20100069355-A1 | Analogs of Indole-3-Carbinol and Their Use as Agents Against Infection | IDO1, IDO2, TDO2 | KMT2A 2912/4885HSD17B10 1780/4885LTA4H 1347/4885 |
| US-20130345214-A1 | Lipoxygenase Inhibitors | ALOX15B, ALOX12, ALOX15 | KMT2A 2705/4885HSD17B10 289/4885LTA4H 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.