SCHEMBL7933280

SCHEMBL7933280

c1ccc(N(Cc2cccc3[nH]nnc23)c2ccccc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.37
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33
NOS2 P35228 1/20 0.31
NR3C2 P08235 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4919621 0.88 CYP2D6 (0.34) TAAR1
SCHEMBL3462446 0.85 TAAR1 (0.40) TAAR1
SCHEMBL534981 0.80 TRPM8 (0.38)
SCHEMBL30080124 0.79 CYP3A4 (0.41)
SCHEMBL283985 0.79 CYP3A4 (0.41)
SCHEMBL11312077 0.77 ALDH1A1 (0.43)
SCHEMBL534923 0.77 ALDH1A1 (0.47)
SCHEMBL284673 0.76 MAPT (0.44)
SCHEMBL9186966 0.76
SCHEMBL29696957 0.76 GPR84 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6184262-B1 Benzotriazole stabilizers for polyols and polyurethane foam R. T. VANDERBILT COMPANY, INC. 2001-02-06 US claimed
EP-0839861-A2 Benzotriazole stabilizers for polyols and polyurethane foam R.T. VANDERBILT COMPANY, Inc. (US) 1998-05-06 EP claimed
US-6184262-B1 Benzotriazole stabilizers for polyols and polyurethane foam R. T. VANDERBILT COMPANY, INC. 2001-02-06 US disclosed
EP-0839861-A3 Benzotriazole stabilizers for polyols and polyurethane foam R.T. VANDERBILT COMPANY, Inc. (US) 1999-12-22 EP disclosed
EP-0839861-A2 Benzotriazole stabilizers for polyols and polyurethane foam R.T. VANDERBILT COMPANY, Inc. (US) 1998-05-06 EP disclosed
EP-0205398-A1 Additive for functional fluids CIBA-GEIGY AG (CH) 1986-12-17 EP disclosed