SCHEMBL346391

SCHEMBL346391

C=CC(=O)O[C@H]1COC(=O)C1(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL998027 1.00
SCHEMBL6721750 0.74 ALDH1A1 (0.39)
SCHEMBL17404435 0.71 SMN1; SMN2 (0.36)
SCHEMBL27608626 0.70
SCHEMBL27552908 0.70
SCHEMBL27716404 0.69
SCHEMBL22309795 0.68 CA2 (0.33)
SCHEMBL685723 0.68 CTSV (0.36)
SCHEMBL9957780 0.68 CTSV (0.36)
SCHEMBL1351991 0.68 CTSV (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8591842-B2 Molecularly imprinted polymer ion exchange resins THE JOHNS HOPKINS UNIVERSITY (US) 2013-11-26 US disclosed
US-20120012530-A1 MOLECULARLY IMPRINTED POLYMER ION EXCHANGE RESINS JOHNS HOPKINS UNIVERSITY (US) 2012-01-19 US disclosed
US-8058208-B2 Beads having properly sized cavities for selective sequestering of specific inorganic ions from liquid medium; suspension copolymerization of styrene, divinylbenzene and reactive complex then removing metal ion; water clean up THE JOHNS HOPKINS UNIVERSITY (US) 2011-11-15 US disclosed
US-20080264868-A1 Molecularly Imprinted Polymer Ion Exchange Resins JOHNS HOPKINS UNIVERSITY 2008-10-30 US disclosed
EP-1948357-A1 MOLECULARLY IMPRINTED POLYMER ION EXCHANGE RESINS The John Hopkins University (US) 2008-07-30 EP disclosed
US-20080144002-A1 Molecularly Imprinted Polymer Sensor Device JOHNS HOPKINS UNIVERSITY 2008-06-19 US disclosed
WO-2007055767-A1 MOLECULARLY IMPRINTED POLYMER ION EXCHANGE RESINS THE JOHNS HOPKINS UNIVERSITY (US) 2007-05-18 WO disclosed