SCHEMBL998027

SCHEMBL998027

C=CC(=O)OC1COC(=O)C1(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL346391 1.00
SCHEMBL6721750 0.74 ALDH1A1 (0.39)
SCHEMBL17404435 0.71 SMN1; SMN2 (0.36)
SCHEMBL27608626 0.70
SCHEMBL27552908 0.70
SCHEMBL27716404 0.69
SCHEMBL22309795 0.68 CA2 (0.33)
SCHEMBL685723 0.68 CTSV (0.36)
SCHEMBL9957780 0.68 CTSV (0.36)
SCHEMBL1351991 0.68 CTSV (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3344232-B1 MICELLES FOR MUCOADHESIVE DRUG DELIVERY UNIV MCMASTER (CA) 2022-01-26 EP claimed
US-20200397697-A1 FORMULATIONS OF TIE-2 ACTIVATORS AND METHODS OF USE THEREOF EyePoint Pharmaceuticals, Inc. 2020-12-24 US claimed
US-10611908-B2 Micelles for mucoadhesive drug delivery MCMASTER UNIVERSITY (CA) 2020-04-07 US claimed
US-20180265694-A1 Micelles for Mucoadhesive Drug Delivery MCMASTER UNIVERSITY (CA) 2018-09-20 US claimed
US-8920841-B2 Biodegradable polymer system SHEARDOWN HEATHER (CA) 2014-12-30 US claimed
US-20110288062-A1 Biodegradable polymer system SHEARDOWN HEATHER (CA) 2011-11-24 US claimed
US-20230139250-A1 FORMULATIONS OF TIE-2 ACTIVATORS AND METHODS OF USE THEREOF EYEPOINT PHARMACEUTICALS INC (US) 2023-05-04 US disclosed
EP-3344232-B1 MICELLES FOR MUCOADHESIVE DRUG DELIVERY UNIV MCMASTER (CA) 2022-01-26 EP disclosed
US-20200397697-A1 FORMULATIONS OF TIE-2 ACTIVATORS AND METHODS OF USE THEREOF EyePoint Pharmaceuticals, Inc. 2020-12-24 US disclosed
US-10611908-B2 Micelles for mucoadhesive drug delivery MCMASTER UNIVERSITY (CA) 2020-04-07 US disclosed
US-10182980-B2 Method of making an amino silicone nanoemulsion THE PROCTER & GAMBLE COMPANY (US) 2019-01-22 US disclosed
US-20180265694-A1 Micelles for Mucoadhesive Drug Delivery MCMASTER UNIVERSITY (CA) 2018-09-20 US disclosed
EP-3250292-A1 A METHOD OF MAKING AN AMINO SILICONE NANOEMULSION The Procter and Gamble Company (US) 2017-12-06 EP disclosed
US-20020146225-A1 Coated optical fibers DSM IP ASSETS B.V. (NL) 2002-10-10 US disclosed
WO-2002042383-A1 RADIATION CURABLE COMPOSITIONS DSM N.V. (NL) 2002-05-30 WO disclosed
WO-2002042237-A2 COATED OPTICAL FIBERS DSM N.V. (NL) 2002-05-30 WO disclosed
US-6177511-B1 ANIONIC, CATIONIC, NONIONIC OR AMPHOTERIC SURFACTANTS; DIACRYLATES AND/OR OLIGOACRYLATES WACKER-CHEMIE GMBH (DE) 2001-01-23 US disclosed
EP-0933399-B1 Aminosilicone oil emulsions crosslinked by Michael addition-type reactions WACKER CHEMIE GMBH (DE) 2000-09-13 EP disclosed
EP-0972811-A1 Radiation curable copolymer compositions Wacker-Chemie GmbH (DE) 2000-01-19 EP disclosed
EP-0933399-A1 Aminosilicone oil emulsions crosslinked by Michael addition-type reactions Wacker-Chemie GmbH (DE) 1999-08-04 EP disclosed