SCHEMBL346416

SCHEMBL346416

COc1ccc(CN)cc1O

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.73
CYP1A2 P05177 1/20 0.73
CYP3A4 P08684 1/20 0.73
NFKB1 P19838 1/20 0.73
LMNA P02545 2/20 0.71
MEN1 O00255 1/20 0.71
APEX1 P27695 1/20 0.71
KMT2A Q03164 1/20 0.71
ALOX15 P16050 1/20 0.62
ALOX12 P18054 1/20 0.62
GAA P10253 1/20 0.61
TUBB4A P04350 5/20 0.59
TUBB P07437 5/20 0.59
TUBA3C P0DPH7 5/20 0.59
TUBA1B P68363 5/20 0.59
TUBA4A P68366 5/20 0.59
TUBB4B P68371 5/20 0.59
TUBB3 Q13509 5/20 0.59
TUBB2A Q13885 5/20 0.59
TUBB8 Q3ZCM7 5/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1143719 0.98 LMNA (0.74) TSHRCYP1A2CYP3A4NFKB1LMNA
Hydrochloric Acid SCHEMBL29679697 0.98 LMNA (0.74) TSHRCYP1A2CYP3A4NFKB1LMNA
Bromide SCHEMBL3713176 0.98 TSHR (0.71) TSHRCYP1A2CYP3A4NFKB1LMNA
Hydrochloric Acid SCHEMBL3570031 0.96 TSHR (0.69) TSHRCYP1A2CYP3A4NFKB1LMNA
SCHEMBL347613 0.85 TSHR (1.00) TSHRCYP1A2CYP3A4NFKB1LMNA
SCHEMBL29351790 0.85 TSHR (1.00) TSHRCYP1A2CYP3A4NFKB1LMNA
SCHEMBL140416 0.84 TSHR (0.76) TSHRCYP1A2CYP3A4NFKB1LMNA
SCHEMBL27127537 0.84 TSHR (0.76) TSHRCYP1A2CYP3A4NFKB1LMNA
SCHEMBL31077499 0.84 TSHR (0.76) TSHRCYP1A2CYP3A4NFKB1LMNA
SCHEMBL69858 0.83 TUBB4A (0.79) TSHRCYP1A2CYP3A4NFKB1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113646479-B Method for strengthening non-keratin fibers and use thereof 埃斯普投资有限公司 2023-06-13 CN claimed
CN-113646479-A Method for strengthening non-keratin fibers and use thereof 埃斯普投资有限公司 2021-11-12 CN claimed
EP-3565523-B1 METHOD FOR COLORING OR BLEACHING HAIR FIBERS HERCULES LLC (US) 2021-09-08 EP claimed
US-20190085007-A1 4-methylcatechol Derivatives and Uses Thereof Thanares GmbH (DE) 2019-03-21 US claimed
US-20180193242-A1 METHOD FOR COLORING OR BLEACHING HAIR FIBERS HERCULES LLC (DE) 2018-07-12 US claimed
US-20160347782-A1 4-methylcatechol Derivatives and Uses Thereof Thanares GmbH (DE) 2016-12-01 US claimed
EP-2593021-A2 BIOADHESIVE COMPOUNDS AND METHODS OF SYNTHESIS AND USE KNC NER Acquisition Sub, Inc. (US) 2013-05-22 EP claimed
WO-2013034119-A1 4-METHYLCATECHOL DERIVATIVES UND USE THEREOF Thanares GmbH (DE) 2013-03-14 WO claimed
US-20120016390-A1 BIOADHESIVE COMPOUNDS AND METHODS OF SYNTHESIS AND USE KNC NER ACQUISITION SUB, INC. (US) 2012-01-19 US claimed
WO-2012009664-A2 BIOADHESIVE COMPOUNDS AND METHODS OF SYNTHESIS AND USE KNC NER ACQUISITION SUB, INC. (US) 2012-01-19 WO claimed
WO-2009141384-A2 PROCESS FOR THE PURIFICATION OF FACTOR VII POLYPEPTIDES USING AFFINITY RESINS COMPRISING SPECIFIC LIGANDS NOVO NORDISK A/S (DK) 2009-11-26 WO claimed
US-20260027090-A1 Methods of Inhibiting Osteoclastogenesis and Osteoclast Activity VTV THERAPEUTICS LLC (US) 2026-01-29 US disclosed
US-20250195671-A1 COVALENT ANESTHETIC-POLYMER CONJUGATES FOR PROLONGED LOCAL ANESTHESIA THE CHILDREN'S MEDICAL CENTER CORPORATION 2025-06-19 US disclosed
EP-3229771-B1 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF UNIV PALACKEHO (CZ) 2024-04-03 EP disclosed
CN-111867633-B Covalent anesthetic-polymer conjugates for achieving prolonged local anesthesia 儿童医学中心公司 2023-09-22 CN disclosed
EP-0680469-A1 AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME Dr. Karl Thomae GmbH (DE) 1995-11-08 EP disclosed
WO-1994017035-A1 AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME DR. KARL THOMAE GMBH (DE) 1994-08-04 WO disclosed
EP-0091385-B1 PROCESS FOR THE PREPARATION OF P-HYDROXYBENZYL NITRILES OR P-HYDROXYBENZYL AMINES RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1985-06-12 EP disclosed
EP-0091385-A1 Process for the preparation of p-hydroxybenzyl nitriles or p-hydroxybenzyl amines RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1983-10-12 EP disclosed
US-4388250-A FROM HYDROXYBENZALDEHYDE RHONE POULENC INC. (US) 1983-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250195671-A1 COVALENT ANESTHETIC-POLYMER CONJUGATES FOR PROLONGED LOCAL ANESTHESIA TNNC1, TNNT2, TNNI3 TSHR 437/4885CYP1A2 1931/4885CYP3A4 1271/4885
US-20180193242-A1 METHOD FOR COLORING OR BLEACHING HAIR FIBERS FHIT, KAT2B, KAT2A TSHR 2204/4885CYP1A2 661/4885CYP3A4 3179/4885
US-20190085007-A1 4-methylcatechol Derivatives and Uses Thereof ST3GAL3, GALE, DPP4 TSHR 4840/4885CYP1A2 241/4885CYP3A4 27/4885
US-20260027090-A1 Methods of Inhibiting Osteoclastogenesis and Osteoclast Activity CSF1R, CD209, NFATC1 TSHR 2548/4885CYP1A2 2748/4885CYP3A4 2312/4885
US-20160347782-A1 4-methylcatechol Derivatives and Uses Thereof ST3GAL3, GALE, DPP4 TSHR 4840/4885CYP1A2 241/4885CYP3A4 27/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.