Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.59 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.51 |
| ▸ | DHFR | P00374 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | DHODH | Q02127 | 2/20 | 0.47 |
| ▸ | ALOX5AP | P20292 | 6/20 | 0.46 |
| ▸ | FEN1 | P39748 | 6/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GCGR | P47871 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3571448 | 0.82 | PTPRC (0.57) | PTPRCNR3C1DHFRL3MBTL1PDE10A | |
| SCHEMBL5025945 | 0.81 | ALOX5AP (0.56) | PTPRCDHFRL3MBTL1ALOX5APFEN1 | |
| SCHEMBL18134264 | 0.80 | FGFR2 (0.45) | PTPRCL3MBTL1FGFR1FGFR2 | |
| SCHEMBL27637475 | 0.80 | L3MBTL1 (0.51) | PTPRCNR3C1DHFRL3MBTL1ALOX5AP | |
| SCHEMBL27324839 | 0.77 | PTPRC (0.58) | PTPRCDHFRL3MBTL1PDE10ATDP1 | |
| SCHEMBL27707593 | 0.76 | PTPRC (0.51) | PTPRCNR3C1DHFRL3MBTL1DHODH | |
| SCHEMBL203121 | 0.76 | ADRB2 (0.61) | PTPRCL3MBTL1TDP1 | |
| SCHEMBL198911 | 0.75 | ALDH1A1 (0.60) | PTPRCL3MBTL1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL12999516 | 0.75 | SYK (0.59) | PTPRCDHFRL3MBTL1PDE10ATDP1 | |
| SCHEMBL21469977 | 0.75 | PTPRC (0.50) | PTPRCNR3C1DHODHALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240678-A1 | LEUKOTRIENE B4 INHIBITORS | DOMINIQUE ROMYR | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240678-A1 | LEUKOTRIENE B4 INHIBITORS | LTB4R2, LTB4R, LTC4S | PTPRC 3180/4885NR3C1 777/4885DHFR 744/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.