Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP3 | P08254 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 2/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3466571 | 0.87 | MMP2 (0.48) | MMP2MMP3ALDH1A1KMT2AMEN1 | |
| SCHEMBL7923945 | 0.87 | MMP2 (0.57) | MMP2MMP3ALDH1A1MAPTKMT2A | |
| SCHEMBL1860059 | 0.86 | MMP12 (0.53) | MMP2MMP3MMEMMP12 | |
| SCHEMBL3466555 | 0.86 | LPAR1 (0.50) | KMT2AMEN1PPARGPPARAFFAR1 | |
| SCHEMBL3466649 | 0.85 | SLC13A5 (0.48) | MMP2MMP3ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL1859940 | 0.85 | GRIK1 (0.51) | MMP2MMP3KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL1858600 | 0.82 | GRIK1 (0.54) | MMP2MMP3KMT2ASMN1; SMN2POLB | |
| SCHEMBL3467613 | 0.82 | PPARA (0.50) | MMP2MMP3PPARGPPARAMME | |
| SCHEMBL3467360 | 0.82 | ALDH1A1 (0.54) | MMP2MMP3ALDH1A1KMT2AMEN1 | |
| SCHEMBL3466739 | 0.82 | MMP2 (0.52) | MMP2MMP3PPARGMMEHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010070076-A1 | ALKANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE AS HDAC INHIBITORS | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2010-06-24 | — | — | WO | claimed |
| WO-2010070076-A1 | ALKANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE AS HDAC INHIBITORS | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2010-06-24 | — | — | WO | disclosed |