Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.57 |
| ▸ | MMP3 | P08254 | 2/20 | 0.57 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3466652 | 0.87 | MMP2 (0.52) | MMP2MMP3PPARGPPARAALDH1A1 | |
| SCHEMBL3467355 | 0.85 | GRIK1 (0.51) | MMP2MMP3GRIK1ALDH1A1HCAR2 | |
| SCHEMBL7924101 | 0.85 | GRIK1 (0.54) | MMP2MMP3PPARGGRIK1MME | |
| SCHEMBL1861903 | 0.84 | GRIK1 (0.59) | MMP2MMP3GRIK1FFAR1MME | |
| SCHEMBL3468514 | 0.84 | SLC13A5 (0.53) | MMP2MMP3PPARGPPARAGRIK1 | |
| SCHEMBL1860416 | 0.83 | GRIK1 (0.68) | MMP2MMP3PPARGPPARAGRIK1 | |
| SCHEMBL3467962 | 0.81 | PPARG (0.54) | PPARGPPARAGRIK1FFAR1MME | |
| SCHEMBL3466957 | 0.81 | FFAR1 (0.51) | MMP2MMP3GRIK1FFAR1MME | |
| SCHEMBL7922577 | 0.80 | PPARG (0.56) | MMP2MMP3PPARGPPARAGRIK1 | |
| SCHEMBL7918296 | 0.80 | MMP2 (0.56) | MMP2MMP3GRIK1HCAR2MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010070076-A1 | ALKANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE AS HDAC INHIBITORS | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2010-06-24 | — | — | WO | disclosed |