Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MMP3 | P08254 | 7/20 | 0.53 |
| ▸ | MMP2 | P08253 | 4/20 | 0.50 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.50 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.50 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.50 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 3/20 | 0.49 |
| ▸ | PDE4A | P27815 | 3/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1858392 | 0.96 | ALDH1A1 (0.57) | ALDH1A1MMP3MMP2PLAAT3PLAAT5 | |
| SCHEMBL1855703 | 0.93 | ALDH1A1 (0.54) | ALDH1A1MMP3MMP2PLAAT3PLAAT5 | |
| SCHEMBL1860059 | 0.92 | MMP12 (0.53) | MMP3MMP2 | |
| SCHEMBL18065681 | 0.91 | ALDH1A1 (0.63) | ALDH1A1MMP3MMP2PLAAT3PLAAT5 | |
| SCHEMBL3467371 | 0.90 | MMP3 (0.58) | ALDH1A1MMP3MMP2PLAAT3PLAAT5 | |
| SCHEMBL3466501 | 0.90 | HCAR2 (0.52) | MMP3KMT2AMEN1 | |
| SCHEMBL1859940 | 0.88 | GRIK1 (0.51) | MMP3MMP2KMT2A | |
| SCHEMBL3467613 | 0.88 | PPARA (0.50) | MMP3MMP2PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL3466571 | 0.88 | MMP2 (0.48) | ALDH1A1MMP3MMP2MMP1KMT2A | |
| SCHEMBL1856368 | 0.87 | PLAAT3 (0.50) | ALDH1A1MMP3MMP2PLAAT3PLAAT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010070076-A1 | ALKANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE AS HDAC INHIBITORS | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2010-06-24 | — | — | WO | claimed |
| WO-2010070076-A1 | ALKANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE AS HDAC INHIBITORS | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2010-06-24 | — | — | WO | disclosed |