Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 5/20 | 0.48 |
| ▸ | TDP2 | O95551 | 2/20 | 0.44 |
| ▸ | PGR | P06401 | 10/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3310077 | 0.76 | KIF11 (0.59) | KIF11TDP2PGR | |
| SCHEMBL3467162 | 0.71 | KIF11 (0.65) | KIF11TDP2PGRNOTUM | |
| SCHEMBL5428163 | 0.70 | KIF11 (0.48) | KIF11TDP2PGRAR | |
| SCHEMBL4898502 | 0.69 | KIF11 (0.50) | KIF11TDP2NOTUMAR | |
| SCHEMBL1396636 | 0.68 | HSPA9 (0.62) | KIF11TDP2PGRAR | |
| SCHEMBL4426124 | 0.67 | PGR (0.62) | KIF11TDP2PGR | |
| SCHEMBL5959182 | 0.67 | EPHX2 (0.51) | KIF11TDP2PGR | |
| SCHEMBL1903306 | 0.66 | KIF11 (0.80) | KIF11TDP2PGR | |
| SCHEMBL4173395 | 0.66 | PGR (0.63) | PGRNR3C1NR3C2AR | |
| SCHEMBL31238638 | 0.65 | PGR (0.54) | PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010074807-A1 | 3, 4-DIHYDROQUINOLIN-2 ( 1H ) -ONE DERIVATIVES AS SODIUM CHANNEL MODULATORS | GILEAD PALO ALTO, INC. (US) | 2010-07-01 | — | — | WO | claimed |