Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR34 | Q9UPC5 | 5/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 8/20 | 0.53 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.53 |
| ▸ | MMP12 | P39900 | 2/20 | 0.52 |
| ▸ | MMP13 | P45452 | 2/20 | 0.52 |
| ▸ | YAP1 | P46937 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.48 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467000 | 0.92 | MMP12 (0.51) | GPR34FFAR1FFAR4AKR1B1MMP12 | |
| SCHEMBL3466325 | 0.91 | FFAR1 (0.57) | GPR34FFAR1FFAR4AKR1B1MMP12 | |
| SCHEMBL3468280 | 0.85 | MMP12 (0.53) | FFAR1FFAR4MMP12MMP13ADAMTS4 | |
| SCHEMBL3467017 | 0.84 | MMP12 (0.57) | FFAR1FFAR4MMP12MMP13ADAMTS4 | |
| SCHEMBL3467249 | 0.84 | MMP12 (0.54) | GPR34FFAR1FFAR4AKR1B1MMP12 | |
| SCHEMBL7924636 | 0.81 | MMP12 (0.65) | GPR34FFAR1FFAR4AKR1B1MMP12 | |
| SCHEMBL1865673 | 0.75 | LTA4H (0.55) | FFAR1FFAR4MMP12LTA4H | |
| SCHEMBL3467200 | 0.75 | MMP12 (0.60) | FFAR1FFAR4MMP12MMP13ADAMTS4 | |
| SCHEMBL1859451 | 0.75 | FFAR1 (0.44) | GPR34FFAR1FFAR4MMP12MMP13 | |
| SCHEMBL3466543 | 0.75 | MMP12 (0.51) | MMP12MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010070076-A1 | ALKANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE AS HDAC INHIBITORS | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2010-06-24 | — | — | WO | claimed |
| WO-2010070076-A1 | ALKANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE AS HDAC INHIBITORS | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2010-06-24 | — | — | WO | disclosed |