Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 2/20 | 0.54 |
| ▸ | MMP13 | P45452 | 2/20 | 0.54 |
| ▸ | GRIK1 | P39086 | 5/20 | 0.46 |
| ▸ | GRIK2 | Q13002 | 5/20 | 0.46 |
| ▸ | MME | P08473 | 2/20 | 0.41 |
| ▸ | P4HB | P07237 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP3 | P08254 | 2/20 | 0.36 |
| ▸ | CTSC | P53634 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3466777 | 1.00 | MMP12 (0.54) | MMP12MMP13GRIK1GRIK2MME | |
| SCHEMBL7923446 | 0.93 | MMP12 (0.57) | MMP12MMP13GRIK1GRIK2MME | |
| SCHEMBL3467200 | 0.86 | MMP12 (0.60) | MMP12MMP13MMEFOLH1XDH | |
| SCHEMBL7924636 | 0.79 | MMP12 (0.65) | MMP12MMP13MMEFOLH1XDH | |
| SCHEMBL7928277 | 0.78 | MMP12 (0.64) | MMP12MMP13GRIK1MMEFOLH1 | |
| SCHEMBL7932591 | 0.77 | MMP12 (0.63) | MMP12MMP13GRIK1MMEFOLH1 | |
| SCHEMBL3468280 | 0.76 | MMP12 (0.53) | MMP12MMP13MMEFOLH1ADAMTS4 | |
| SCHEMBL3465875 | 0.72 | MMP12 (0.65) | MMP12MMP13MMEXDHSLC22A12 | |
| SCHEMBL1857647 | 0.72 | GRIK1 (0.60) | GRIK1GRIK2 | |
| SCHEMBL1857645 | 0.72 | GRIK1 (0.60) | GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010070076-A1 | ALKANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE AS HDAC INHIBITORS | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2010-06-24 | — | — | WO | claimed |
| WO-2010070076-A1 | ALKANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE AS HDAC INHIBITORS | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2010-06-24 | — | — | WO | disclosed |