Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 3/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CTSA | P10619 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 3/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.35 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2118158 | 0.82 | ACLY (0.55) | ACLYALPLHSD11B1 | |
| SCHEMBL3467342 | 0.76 | ACLY (0.45) | ACLYCTSAALPLHSD11B1 | |
| SCHEMBL3467338 | 0.73 | CTSA (0.38) | ACLYCTSAALPL | |
| SCHEMBL2117509 | 0.71 | ACLY (0.42) | ACLYMEN1KMT2AALPL | |
| SCHEMBL13802320 | 0.65 | AR (0.50) | ACLYCTSA | |
| SCHEMBL3467313 | 0.64 | KATNA1 (0.35) | CTSA | |
| SCHEMBL2119329 | 0.64 | GHSR (0.45) | ACLYMEN1KMT2A | |
| SCHEMBL5166693 | 0.63 | NR3C2 (0.57) | ACLYCNR1NR3C2 | |
| SCHEMBL5892016 | 0.63 | CYP19A1 (0.57) | CNR1NR3C2ALPLCYP19A1 | |
| SCHEMBL7280551 | 0.61 | ACLY (0.53) | ACLYALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010076034-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE AS-INHIBITORS | EUROPEAN MOLECULAR BIOLOGY LABORATORY (EMBL) (DE) | 2010-07-08 | — | — | WO | disclosed |