Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 1/20 | 0.38 |
| ▸ | ACLY | P53396 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | POLQ | O75417 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467309 | 0.88 | SYK (0.36) | CTSASMN1; SMN2PARP1ALDH1A1L3MBTL1 | |
| SCHEMBL3467342 | 0.83 | ACLY (0.45) | CTSAACLYALPLRXFP1 | |
| SCHEMBL3713934 | 0.79 | PARP1 (0.50) | PARP1IRAK4CASP1CA12CA1 | |
| SCHEMBL2118158 | 0.75 | ACLY (0.55) | ACLYSMN1; SMN2ALPL | |
| SCHEMBL3467313 | 0.75 | KATNA1 (0.35) | CTSAALDH1A1L3MBTL1PRKDC | |
| SCHEMBL3467341 | 0.73 | ACLY (0.43) | CTSAACLYALPL | |
| SCHEMBL3466612 | 0.72 | CA2 (0.36) | SMN1; SMN2ALDH1A1CA2 | |
| SCHEMBL14136790 | 0.68 | CASP1 (0.44) | PARP1ALDH1A1CASP1PRKDC | |
| SCHEMBL6027291 | 0.68 | ACLY (0.50) | CTSAACLYALDH1A1CA12CA1 | |
| SCHEMBL3996717 | 0.67 | CFD (0.51) | CTSAACLYSMN1; SMN2ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010076034-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE AS-INHIBITORS | EUROPEAN MOLECULAR BIOLOGY LABORATORY (EMBL) (DE) | 2010-07-08 | — | — | WO | disclosed |