Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 6/20 | 0.45 |
| ▸ | CTSA | P10619 | 1/20 | 0.37 |
| ▸ | BRD1 | O95696 | 3/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 3/20 | 0.35 |
| ▸ | BRPF3 | Q9ULD4 | 3/20 | 0.35 |
| ▸ | ALPL | P05186 | 3/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2118158 | 0.84 | ACLY (0.55) | ACLYBRD1BRPF1BRPF3ALPL | |
| SCHEMBL3467338 | 0.83 | CTSA (0.38) | ACLYCTSAALPLRXFP1 | |
| SCHEMBL3713935 | 0.76 | KIF11 (0.43) | ACLYHSD11B1 | |
| SCHEMBL3467341 | 0.76 | ACLY (0.43) | ACLYCTSAALPLHSD11B1 | |
| SCHEMBL3467313 | 0.74 | KATNA1 (0.35) | CTSAFLT1FLT4KDR | |
| SCHEMBL3466612 | 0.73 | CA2 (0.36) | — | |
| SCHEMBL2117509 | 0.73 | ACLY (0.42) | ACLYBRD1BRPF1BRPF3ALPL | |
| SCHEMBL3467309 | 0.72 | SYK (0.36) | CTSA | |
| SCHEMBL6027291 | 0.69 | ACLY (0.50) | ACLYCTSAALPLHSD11B1 | |
| SCHEMBL2119329 | 0.66 | GHSR (0.45) | ACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010076034-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE AS-INHIBITORS | EUROPEAN MOLECULAR BIOLOGY LABORATORY (EMBL) (DE) | 2010-07-08 | — | — | WO | disclosed |