Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KATNA1 | O75449 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | CTSA | P10619 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467309 | 0.88 | SYK (0.36) | KDM1ACTSAHPGDKDM4EALDH1A1 | |
| SCHEMBL2117509 | 0.80 | ACLY (0.42) | KDM4EALDH1A1FLT1FLT4KDR | |
| SCHEMBL3467724 | 0.78 | CYP11B1 (0.47) | KDM1AHPGDKDM4EALDH1A1HTT | |
| SCHEMBL3467338 | 0.75 | CTSA (0.38) | CTSAALDH1A1L3MBTL1PRKDC | |
| SCHEMBL3467342 | 0.74 | ACLY (0.45) | CTSAFLT1FLT4KDR | |
| SCHEMBL3466612 | 0.69 | CA2 (0.36) | ALDH1A1HTT | |
| SCHEMBL2117577 | 0.68 | MAPT (0.45) | KDM4EALDH1A1 | |
| SCHEMBL3467721 | 0.66 | CASP1 (0.49) | KDM1AHPGDKDM4EALDH1A1HTT | |
| SCHEMBL2118158 | 0.66 | ACLY (0.55) | — | |
| SCHEMBL3466792 | 0.66 | CYP11B1 (0.49) | KATNA1KDM1AKITCYP11B1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010076034-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE AS-INHIBITORS | EUROPEAN MOLECULAR BIOLOGY LABORATORY (EMBL) (DE) | 2010-07-08 | — | — | WO | disclosed |