Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467352 | 0.87 | KIF11 (0.45) | KIF11FFAR1 | |
| SCHEMBL3467503 | 0.81 | KIF11 (0.44) | KIF11MAPTFFAR1 | |
| SCHEMBL3468115 | 0.79 | KIF11 (0.47) | KIF11FFAR1 | |
| SCHEMBL4596470 | 0.77 | KIF11 (0.49) | KIF11MAPTGPBAR1TSHR | |
| SCHEMBL4891219 | 0.75 | KIF11 (0.56) | KIF11FFAR1 | |
| SCHEMBL3308412 | 0.74 | KIF11 (0.53) | KIF11 | |
| SCHEMBL3468263 | 0.74 | KIF11 (0.53) | KIF11FFAR1 | |
| SCHEMBL3467771 | 0.74 | KIF11 (0.48) | KIF11FFAR1 | |
| SCHEMBL3467592 | 0.73 | KIF11 (0.52) | KIF11 | |
| SCHEMBL3308461 | 0.73 | MAPT (0.48) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010074807-A1 | 3, 4-DIHYDROQUINOLIN-2 ( 1H ) -ONE DERIVATIVES AS SODIUM CHANNEL MODULATORS | GILEAD PALO ALTO, INC. (US) | 2010-07-01 | — | — | WO | disclosed |