Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA4 | P22748 | 2/20 | 0.34 |
| ▸ | CA5A | P35218 | 2/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1094685 | 0.81 | APOBEC3G (0.47) | APOBEC3GKMT2APOLBALDH1A1TSHR | |
| SCHEMBL15884499 | 0.81 | NR1I2 (0.44) | APOBEC3GKMT2APOLBALDH1A1TSHR | |
| SCHEMBL1093933 | 0.77 | KDM4E (0.49) | APOBEC3GKMT2APOLBALDH1A1TSHR | |
| SCHEMBL5181888 | 0.74 | ALDH1A1 (0.41) | APOBEC3GKMT2APOLBALDH1A1TSHR | |
| SCHEMBL294183 | 0.74 | ALDH1A1 (0.51) | APOBEC3GKMT2APOLBALDH1A1TSHR | |
| SCHEMBL16180374 | 0.71 | ESR1 (0.54) | POLBALDH1A1HSD17B10 | |
| SCHEMBL6432835 | 0.69 | APOBEC3G (0.52) | APOBEC3GKMT2AALDH1A1TSHRCA1 | |
| SCHEMBL22257152 | 0.69 | APOBEC3G (0.52) | APOBEC3GKMT2AALDH1A1TSHRCA1 | |
| SCHEMBL9735258 | 0.68 | KMT2A (0.50) | APOBEC3GKMT2AALDH1A1CA1CA2 | |
| Benzenesulfonamide SCHEMBL11048441 | 0.67 | CA2 (0.55) | KMT2APOLBCA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | disclosed |