Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | TERT | O14746 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3909238 | 0.83 | L3MBTL1 (0.69) | L3MBTL1ALDH1A1MAPTHTTTSHR | |
| SCHEMBL9871889 | 0.81 | ALDH1A1 (0.62) | L3MBTL1ALDH1A1LMNAMAPTTP53 | |
| SCHEMBL10436938 | 0.81 | ALDH1A1 (0.63) | L3MBTL1ALDH1A1LMNAMAPTTP53 | |
| SCHEMBL8779333 | 0.78 | ALDH1A1 (0.60) | ALDH1A1LMNAMAPTTP53HTT | |
| SCHEMBL3909233 | 0.77 | L3MBTL1 (0.61) | L3MBTL1ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL3467663 | 0.76 | CA1 (0.74) | L3MBTL1ALDH1A1LMNAMAPTTP53 | |
| SCHEMBL3263155 | 0.70 | LMNA (0.72) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL8779340 | 0.69 | CYP1A2 (0.77) | ALDH1A1LMNAMAPTHTTMEN1 | |
| SCHEMBL6404293 | 0.68 | KDM4E (0.63) | ALDH1A1LMNAMAPTHTTMEN1 | |
| SCHEMBL9456833 | 0.67 | CYP1A2 (0.59) | L3MBTL1ALDH1A1MAPTTP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | claimed |