Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | KYNU | Q16719 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
| ▸ | PRTN3 | P24158 | 2/20 | 0.42 |
| ▸ | CTSL | P07711 | 3/20 | 0.42 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.42 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL56584 | 0.86 | HDAC1 (0.52) | HDAC1HDAC2KYNURAB9AELANE | |
| SCHEMBL346475 | 0.83 | MEN1 (0.46) | KYNURAB9AELANEPRTN3CTSL | |
| SCHEMBL345272 | 0.82 | GRM8 (0.58) | HDAC1HDAC2KYNURAB9ACTSL | |
| SCHEMBL345271 | 0.82 | GRM8 (0.58) | HDAC1HDAC2KYNURAB9ACTSL | |
| SCHEMBL10000466 | 0.81 | GRM8 (0.56) | HDAC1HDAC2KYNURAB9ACTSL | |
| SCHEMBL346780 | 0.79 | GRM8 (0.54) | HDAC1HDAC2KYNURAB9ACTSL | |
| SCHEMBL346779 | 0.79 | GRM8 (0.54) | HDAC1HDAC2KYNURAB9ACTSL | |
| SCHEMBL56268 | 0.77 | HDAC1 (0.54) | HDAC1HDAC2ELANEPRTN3CTSL | |
| SCHEMBL56740 | 0.76 | HDAC1 (0.50) | HDAC1HDAC2KYNUELANEPRTN3 | |
| SCHEMBL13774905 | 0.76 | GRM8 (0.52) | HDAC1HDAC2KYNUCTSLGSTP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408789-A1 | DIASTEREOISOMERS OF HYPOPHOSPHOROUS ACID DERIVATIVES | Centre National De La Recherche Scientifique CNRS (FR) | 2012-01-25 | — | — | EP | disclosed |
| US-20120016155-A1 | DIASTEREOISOMERS OF HYPOPHOSPHOROUS ACID DERIVATIVES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2012-01-19 | — | — | US | disclosed |
| WO-2010106526-A1 | DIASTEREOISOMERS OF HYPOPHOSPHOROUS ACID DERIVATIVES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2010-09-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120016155-A1 | DIASTEREOISOMERS OF HYPOPHOSPHOROUS ACID DERIVATIVES | PTH1R, P4HA1, FGF23 | HDAC1 1441/4885HDAC2 1369/4885KYNU 1051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.