Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.41 |
| ▸ | MMP3 | P08254 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3466502 | 0.90 | MAPK1 (0.42) | MAPK1DHODHGRIK1FFAR4MMP3 | |
| SCHEMBL3467962 | 0.83 | PPARG (0.54) | GRIK1FFAR1PTGESALOX5PPARG | |
| SCHEMBL3466023 | 0.82 | MAPK1 (0.45) | MAPK1DHODHFFAR4MMP3MMP2 | |
| SCHEMBL3467371 | 0.79 | MMP3 (0.58) | GRIK1MMP3ALOX5MMP2 | |
| SCHEMBL8041638 | 0.79 | GRIK1 (0.56) | MAPK1GRIK1MMP3MMP2 | |
| SCHEMBL3467355 | 0.78 | GRIK1 (0.51) | GRIK1MMP3MMP2 | |
| SCHEMBL1856418 | 0.77 | ALDH1A1 (0.56) | GRIK1MMP3ALOX5MMP2 | |
| SCHEMBL1861903 | 0.77 | GRIK1 (0.59) | GRIK1MMP3FFAR1MMP2 | |
| SCHEMBL7923945 | 0.77 | MMP2 (0.57) | GRIK1MMP3FFAR1PPARGMMP2 | |
| SCHEMBL1860416 | 0.75 | GRIK1 (0.68) | MAPK1GRIK1MMP3PTGESALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010070076-A1 | ALKANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE AS HDAC INHIBITORS | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2010-06-24 | — | — | WO | disclosed |