Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.54 |
| ▸ | CTSS | P25774 | 7/20 | 0.51 |
| ▸ | CTSL | P07711 | 6/20 | 0.51 |
| ▸ | CTSB | P07858 | 4/20 | 0.51 |
| ▸ | TACR1 | P25103 | 2/20 | 0.49 |
| ▸ | GLS | O94925 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7760223 | 0.89 | CASP1 (0.58) | CTSKCTSSCTSLCASP1 | |
| SCHEMBL23006720 | 0.87 | CTRB1 (0.57) | CTSKCTSSCTSLCTSBMEN1 | |
| SCHEMBL9115465 | 0.86 | CASP1 (0.55) | CTSKCASP1 | |
| SCHEMBL23039999 | 0.85 | CTSK (0.59) | CTSKCTSSCTSLCTSBTACR1 | |
| SCHEMBL23040001 | 0.85 | CTSK (0.59) | CTSKCTSSCTSLCTSBTACR1 | |
| SCHEMBL23058683 | 0.84 | CTSK (0.58) | CTSKCTSSCTSLCTSBTACR1 | |
| SCHEMBL31248222 | 0.84 | CTSK (0.58) | CTSKCTSSCTSLCTSBTACR1 | |
| SCHEMBL23055151 | 0.84 | CTSK (0.58) | CTSKCTSSCTSLCTSBTACR1 | |
| SCHEMBL6826924 | 0.82 | KYNU (0.59) | CTSKCTSSCTSLCTSBTACR1 | |
| SCHEMBL1760460 | 0.82 | KYNU (0.59) | CTSKCTSSCTSLCTSBTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010148300-A1 | METHODS OF TREATMENT OF NEUROLOGICAL DISORDERS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2010-12-23 | — | — | WO | disclosed |