Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 13/20 | 0.58 |
| ▸ | CASP3 | P42574 | 4/20 | 0.53 |
| ▸ | CASP7 | P55210 | 4/20 | 0.53 |
| ▸ | CASP4 | P49662 | 2/20 | 0.53 |
| ▸ | CASP9 | P55211 | 2/20 | 0.53 |
| ▸ | CASP10 | Q92851 | 2/20 | 0.53 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.53 |
| ▸ | CTSK | P43235 | 3/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | CTSS | P25774 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9115465 | 0.97 | CASP1 (0.55) | CASP1CASP3CASP7CASP4CASP9 | |
| SCHEMBL3468362 | 0.89 | CTSK (0.54) | CASP1CTSKCTSLCTSS | |
| SCHEMBL23006720 | 0.86 | CTRB1 (0.57) | CTSKCTSLCTSS | |
| SCHEMBL7764455 | 0.85 | MMP9 (0.65) | CASP1CASP3CASP7CASP4CASP9 | |
| SCHEMBL7764419 | 0.85 | MMP9 (0.65) | CASP1CASP3CASP7CASP4CASP9 | |
| SCHEMBL16770335 | 0.83 | CASP3 (0.59) | CASP1CASP3CASP7CASP4CASP9 | |
| SCHEMBL10789378 | 0.82 | MME (0.62) | CASP1CASP3CASP7CASP9CTSK | |
| SCHEMBL10453892 | 0.81 | CAPN1 (0.61) | CASP1CTSK | |
| SCHEMBL6955527 | 0.81 | CASP1 (0.60) | CASP1CTSLCTSS | |
| SCHEMBL6156731 | 0.81 | CASP1 (0.60) | CASP1CTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0845455-B1 | Addition salts of N-acyl aspartic acid and alpha-arylalkylamines and process for the optical resolution of alpha-arylalkylamines | AJINOMOTO KK (JP) | 2001-05-16 | — | — | EP | disclosed |
| EP-0688760-B1 | Addition salts of acyl-amino acids and alpha-aryl-amines and process for the optical resolution of alpha-arylamines | AJINOMOTO KK (JP) | 1999-06-09 | — | — | EP | disclosed |
| EP-0845455-A1 | Addition salts of acyl-amino acids and alpha-arylamines and process for the optical resolution of alpha-arylamines | Ajinomoto Co., Inc. (JP) | 1998-06-03 | — | — | EP | disclosed |
| EP-0688760-A1 | Addition salts of acyl-amino acids and alpha-aryl-amines and process for the optical resolution of alpha-arylamines | Ajinomoto Co., Inc. (JP) | 1995-12-27 | — | — | EP | disclosed |