Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.32 |
| ▸ | BRD2 | P25440 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3469011 | 0.84 | HDAC8 (0.42) | HDAC8HDAC6HSP90AA1MEN1POLB | |
| SCHEMBL13283057 | 0.82 | AGTR1 (0.31) | CASRAGTR1AGTR2 | |
| SCHEMBL3209051 | 0.77 | HDAC8 (0.44) | HDAC8HDAC6HSP90AA1MEN1KMT2A | |
| SCHEMBL3468902 | 0.70 | ALDH1A1 (0.32) | MEN1KMT2AKDM4ELMNAAGTR1 | |
| SCHEMBL3469018 | 0.70 | KCNA3 (0.32) | POLBKDM4EAGTR1AGTR2 | |
| SCHEMBL3226436 | 0.70 | LMNA (0.35) | HDAC8HDAC6MEN1POLBKMT2A | |
| SCHEMBL14025412 | 0.70 | ALDH1A1 (0.43) | HDAC8HDAC6BRD4HTTKDM4E | |
| SCHEMBL3468976 | 0.68 | HDAC8 (0.42) | HDAC8HDAC6BRD4HTTKDM4E | |
| SCHEMBL2870986 | 0.68 | BACE1 (0.42) | HDAC8HDAC6KDM4ELMNA | |
| SCHEMBL3469030 | 0.65 | TYR (0.32) | MEN1KMT2AHTTKDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081835-A2 | BIS-RESORCINYL-TRIAZINE DERIVATIVES AS PROTECTING AGENTS AGAINST UV RADIATION | ISDIN, S. A. (ES) | 2010-07-22 | — | — | WO | disclosed |