Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | BRD2 | P25440 | 1/20 | 0.39 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.39 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14025412 | 0.82 | ALDH1A1 (0.43) | HDAC8HDAC6ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL14025439 | 0.77 | KCNH3 (0.49) | ALDH1A1KDM4EL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL28110914 | 0.74 | CYP11B1 (0.55) | HDAC8HDAC6ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL3209051 | 0.74 | HDAC8 (0.44) | HDAC8HDAC6ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL3219439 | 0.73 | DHFR (0.43) | HDAC8HDAC6ALDH1A1L3MBTL1CYP11B1 | |
| SCHEMBL3469011 | 0.71 | HDAC8 (0.42) | HDAC8HDAC6ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL3230531 | 0.71 | L3MBTL1 (0.43) | ALDH1A1KDM4EL3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL3226440 | 0.70 | KCNH3 (0.40) | HDAC8HDAC6ALDH1A1L3MBTL1HTT | |
| SCHEMBL3226446 | 0.70 | KCNH3 (0.40) | HDAC8HDAC6ALDH1A1L3MBTL1HTT | |
| SCHEMBL27913383 | 0.70 | ALDH1A1 (0.53) | HDAC8HDAC6ALDH1A1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081835-A2 | BIS-RESORCINYL-TRIAZINE DERIVATIVES AS PROTECTING AGENTS AGAINST UV RADIATION | ISDIN, S. A. (ES) | 2010-07-22 | — | — | WO | disclosed |
| US-20080253978-A1 | Derivatives of Pyrrolyltriazine Together with Methods for Obtaining Them and Their Use as Protecting Agents Uv Radiation | ISDIN, S.A. (ES) | 2008-10-16 | — | — | US | disclosed |
| US-20080253978-A1 | Derivatives of Pyrrolyltriazine Together with Methods for Obtaining Them and Their Use as Protecting Agents Uv Radiation | ISDIN, S.A. (ES) | 2008-10-16 | — | — | US | disclosed |
| US-20080253978-A1 | Derivatives of Pyrrolyltriazine Together with Methods for Obtaining Them and Their Use as Protecting Agents Uv Radiation | ISDIN, S.A. (ES) | 2008-10-16 | — | — | US | disclosed |
| EP-1891050-A1 | NEW DERIVATIVES OF PYRROLYLTRIAZINE TOGETHER WITH METHODS FOR OBTAINING THEM AND THEIR USE AS PROTECTING AGENTS AGAINST UV RADIATION | ISDIN, S.A. (ES) | 2008-02-27 | — | — | EP | disclosed |
| WO-2006128920-A1 | NEW DERIVATIVES OF PYRROLYLTRIAZINE TOGETHER WITH METHODS FOR OBTAINING THEM AND THEIR USE AS PROTECTING AGENTS AGAINST UV RADIATION | ISDIN, S.A. (ES) | 2006-12-07 | — | — | WO | disclosed |
| WO-2006128791-A1 | NEW DERIVATIVES OF PYRROLYLTRIAZINE TOGETHER WITH METHODS FOR OBTAINING THEM AND THEIR USE AS PROTECTING AGENTS AGAINST UV RADIATION | ISDIN, S.A. (ES) | 2006-12-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080253978-A1 | Derivatives of Pyrrolyltriazine Together with Methods for Obtaining Them and Their Use as Protecting Agents Uv Radiation | UNG, TPMT, PPOX | HDAC8 3780/4885HDAC6 2724/4885ALDH1A1 891/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.