SCHEMBL3468977

SCHEMBL3468977

O=C1CCC(=O)N1SCCO

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12485891 0.76 BRD4 (0.31)
SCHEMBL20503180 0.73 FAAH (0.36)
SCHEMBL5846148 0.73 KMT2A (0.33) POLB
SCHEMBL29360862 0.71 MGLL (0.33) LMNA
SCHEMBL5847509 0.71 FAAH (0.39) POLB
SCHEMBL13284327 0.70 CHRM2 (0.30)
SCHEMBL11089620 0.70 LMNA (0.31) LMNA
SCHEMBL3626814 0.70 MGLL (0.41) POLB
SCHEMBL10794655 0.70 MGLL (0.41) POLB
SCHEMBL15766022 0.70 PHGDH (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2150176-A1 IMPLANTABLE CONCENTRATION SENSOR AND DEVICE St. Jude Medical AB (SE) 2010-02-10 EP claimed
WO-2008133551-A1 IMPLANTABLE CONCENTRATION SENSOR AND DEVICE ST. JUDE MEDICAL AB (SE) 2008-11-06 WO claimed
EP-2150176-A1 IMPLANTABLE CONCENTRATION SENSOR AND DEVICE St. Jude Medical AB (SE) 2010-02-10 EP disclosed
WO-2008133551-A1 IMPLANTABLE CONCENTRATION SENSOR AND DEVICE ST. JUDE MEDICAL AB (SE) 2008-11-06 WO disclosed