Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5846372 | 0.82 | KMT2A (0.30) | KMT2A | |
| SCHEMBL3468977 | 0.73 | POLB (0.31) | POLB | |
| SCHEMBL12485891 | 0.73 | BRD4 (0.31) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL14408262 | 0.71 | CHRM2 (0.46) | KMT2ACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL20503180 | 0.70 | FAAH (0.36) | KMT2ACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL5081884 | 0.69 | L3MBTL1 (0.46) | KMT2ACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL5810929 | 0.68 | ALDH1A1 (0.42) | KMT2ACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL919534 | 0.68 | DRD3 (0.45) | KMT2ACYP1A2CYP2C19CYP2D6ALDH1A1 | |
| SCHEMBL5847509 | 0.68 | FAAH (0.39) | KMT2ACYP1A2CYP2C19CYP2C9POLB | |
| SCHEMBL3988129 | 0.68 | CHRM2 (0.47) | KMT2ACHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12492220-B2 | Method for the preparation of oligonucleotides | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2025-12-09 | — | — | US | claimed |
| US-20230192751-A1 | METHOD FOR THE PREPARATION OF OLIGONUCLEOTIDES | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIV (CA) | 2023-06-22 | — | — | US | claimed |
| US-5708161-A | Nucleoside phosphorothioate derivatives, synthesis and use thereof | KING'S COLLEGE LONDON (GB) | 1998-01-13 | — | — | US | claimed |
| US-12492220-B2 | Method for the preparation of oligonucleotides | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2025-12-09 | — | — | US | disclosed |
| CN-113631564-B | Method for producing oligonucleotide having phosphorothioate site | 味之素株式会社 | 2025-02-25 | — | — | CN | disclosed |
| US-20230192751-A1 | METHOD FOR THE PREPARATION OF OLIGONUCLEOTIDES | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIV (CA) | 2023-06-22 | — | — | US | disclosed |
| US-11548910-B2 | Oligonucleotide production method | NISSAN CHEMICAL CORPORATION (JP) | 2023-01-10 | — | — | US | disclosed |
| EP-3950698-A1 | METHOD FOR PRODUCING OLIGONUCLEOTIDE HAVING PHOSPHOROTHIOATE SITE | AJINOMOTO CO., INC. (JP) | 2022-02-09 | — | — | EP | disclosed |
| US-20220010348-A1 | METHOD FOR PRODUCING OLIGONUCLEOTIDE HAVING PHOSPHOROTHIOATED SITE | AJINOMOTO CO., INC. (JP) | 2022-01-13 | — | — | US | disclosed |
| US-20190169223-A1 | OLIGONUCLEOTIDE PRODUCTION METHOD | NISSAN CHEMICAL CORPORATION (JP) | 2019-06-06 | — | — | US | disclosed |
| EP-3378869-A1 | METHOD FOR PRODUCING OLIGONUCLEOTIDE | Nissan Chemical Corporation (JP) | 2018-09-26 | — | — | EP | disclosed |
| US-7022833-B2 | Process for the preparation of phosphorothioate triesters | AVECIA LIMITED (GB) | 2006-04-04 | — | — | US | disclosed |
| EP-1272501-B1 | PROCESS FOR THE PREPARATION OF PHOSPHOROTHIOATE TRIESTERS | AVECIA LTD (GB) | 2004-05-06 | — | — | EP | disclosed |
| US-20030099981-A1 | Process for the preparation of phosphorothioate triesters | NITTO DENKO AVECIA, INC. | 2003-05-29 | — | — | US | disclosed |
| EP-1272501-A1 | PROCESS FOR THE PREPARATION OF PHOSPHOROTHIOATE TRIESTERS | Avecia Limited (GB) | 2003-01-08 | — | — | EP | disclosed |
| WO-2001064702-A1 | PROCESS FOR THE PREPARATION OF PHOSPHOROTHIOATE TRIESTERS | AVECIA LIMITED (GB) | 2001-09-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220010348-A1 | METHOD FOR PRODUCING OLIGONUCLEOTIDE HAVING PHOSPHOROTHIOATED SITE | RNGTT, NUDT1, ADAR | KMT2A 2596/4885CHRM2 4872/4885CHRM4 4836/4885 |
| US-11548910-B2 | Oligonucleotide production method | RNGTT, OSGEP, PHAX | KMT2A 2395/4885CHRM2 4882/4885CHRM4 4736/4885 |
| US-20190169223-A1 | OLIGONUCLEOTIDE PRODUCTION METHOD | RNGTT, OSGEP, PHAX | KMT2A 2395/4885CHRM2 4882/4885CHRM4 4736/4885 |
| US-20030099981-A1 | Process for the preparation of phosphorothioate triesters | OSGEP, NUDT1, PNKP | KMT2A 2625/4885CHRM2 4766/4885CHRM4 4194/4885 |
| US-12492220-B2 | Method for the preparation of oligonucleotides | POLN, POLRMT, POLI | KMT2A 3340/4885CHRM2 4878/4885CHRM4 4408/4885 |
| US-20230192751-A1 | METHOD FOR THE PREPARATION OF OLIGONUCLEOTIDES | POLN, POLRMT, POLI | KMT2A 3340/4885CHRM2 4878/4885CHRM4 4408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.