Glycerin

Glycerin

SCHEMBL3469284

O=C(O)CCO.OCC(O)CO

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.50
ALDH1A1 P00352 1/20 0.50
CAMK2A Q9UQM7 1/20 0.46
ALKBH5 Q6P6C2 1/20 0.42
SUCNR1 Q9BXA5 1/20 0.42
EGLN1 Q9GZT9 1/20 0.42
FFAR1 O14842 2/20 0.42
FFAR4 Q5NUL3 2/20 0.42
GPR84 Q9NQS5 1/20 0.42
SLC22A6 Q4U2R8 2/20 0.41
THRB P10828 1/20 0.41
TET2 Q6N021 3/20 0.40
KDM4A O75164 2/20 0.40
KDM4C Q9H3R0 2/20 0.40
KDM2A Q9Y2K7 2/20 0.40
TET3 O43151 1/20 0.40
OR51E2 Q9H255 1/20 0.39
TSHR P16473 1/20 0.36
NFKB1 P19838 1/20 0.36
PMP22 Q01453 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Succinic Acid SCHEMBL6854426 0.88 LMNA (0.56) LMNAALDH1A1CAMK2AALKBH5SUCNR1
Succinic Acid SCHEMBL19478236 0.88 LMNA (0.56) LMNAALDH1A1CAMK2AALKBH5SUCNR1
Succinic Acid SCHEMBL321511 0.88 LMNA (0.56) LMNAALDH1A1CAMK2AALKBH5SUCNR1
Succinic Acid SCHEMBL29758477 0.88 LMNA (0.56) LMNAALDH1A1CAMK2AALKBH5SUCNR1
Succinic Acid SCHEMBL7186939 0.86 LMNA (0.53) LMNAALDH1A1CAMK2AALKBH5SUCNR1
Oxybate SCHEMBL5701250 0.84 CAMK2A (0.70) LMNAALDH1A1CAMK2AFFAR1FFAR4
Adipic Acid SCHEMBL3975352 0.84 FFAR1 (0.56) LMNAALDH1A1CAMK2AFFAR1FFAR4
Glutarate SCHEMBL22490703 0.83 SLC22A6 (0.61) LMNAALDH1A1CAMK2AALKBH5SUCNR1
Adipic Acid SCHEMBL28688445 0.83 LMNA (0.61) LMNAALDH1A1CAMK2AFFAR1FFAR4
Adipic Acid SCHEMBL270756 0.83 LMNA (0.61) LMNAALDH1A1CAMK2AFFAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116209696-A Process for preparing polyglycerol esters of 3-hydroxybutyric acid crosslinked with polycarboxylic acids IOI油脂化学品有限责任公司 2023-06-02 CN claimed
CN-104611383-A Preparation method of recombinant organism 3-hydracrylic acid XINCHANG GUANYANG TECH DEV CO 2015-05-13 CN claimed
EP-2175024-A2 Microbiological production of 3-hydroxypropionic acid Evonik Degussa GmbH (DE) 2010-04-14 EP claimed
EP-1934352-A2 MICROBIOLOGICAL PRODUCTION OF 3-HYDROXYPROPIONIC ACID Degussa GmbH (DE) 2008-06-25 EP claimed
WO-2007042494-A2 MICROBIOLOGICAL PRODUCTION OF 3-HYDROXYPROPIONIC ACID EVONIK DEGUSSA GMBH (DE) 2007-04-19 WO claimed
CN-105358518-B Method for producing acrylic acid from glycerol LG化学株式会社 2017-03-29 CN disclosed
CN-104611383-A Preparation method of recombinant organism 3-hydracrylic acid XINCHANG GUANYANG TECH DEV CO 2015-05-13 CN disclosed
EP-2175024-B1 Microbiological production of 3-hydroxypropionic acid EVONIK DEGUSSA GMBH (DE) 2013-12-04 EP disclosed
EP-2175024-A2 Microbiological production of 3-hydroxypropionic acid Evonik Degussa GmbH (DE) 2010-04-14 EP disclosed
US-20090023182-A1 COMPLEMENTARY METABOLIZING ORGANISMS AND METHODS OF MAKING SAME GENOMATICA, INC. 2009-01-22 US disclosed
EP-1934352-A2 MICROBIOLOGICAL PRODUCTION OF 3-HYDROXYPROPIONIC ACID Degussa GmbH (DE) 2008-06-25 EP disclosed
WO-2007042494-A2 MICROBIOLOGICAL PRODUCTION OF 3-HYDROXYPROPIONIC ACID EVONIK DEGUSSA GMBH (DE) 2007-04-19 WO disclosed