Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7649546 | 0.88 | PDE4B (0.43) | BACE1ESR2HTTLMNAALDH1A1 | |
| SCHEMBL4274830 | 0.85 | PDE4B (0.44) | BACE1ESR2HTTLMNAALDH1A1 | |
| SCHEMBL9721459 | 0.84 | MAPT (0.47) | ESR2HTTLMNAALDH1A1KDM4E | |
| SCHEMBL27957734 | 0.82 | PDE4B (0.50) | BACE1ESR2HTTLMNAALDH1A1 | |
| SCHEMBL19765509 | 0.79 | ACHE (0.48) | ESR2HTTLMNAALDH1A1KDM4E | |
| SCHEMBL1860044 | 0.79 | HTT (0.50) | BACE1ESR2HTTLMNAALDH1A1 | |
| SCHEMBL982859 | 0.78 | TRPA1 (0.44) | BACE1ESR2HTTLMNAALDH1A1 | |
| SCHEMBL7517676 | 0.78 | BACE1 (0.46) | BACE1ESR2HTTALDH1A1PDE4B | |
| SCHEMBL27846611 | 0.78 | CYP2A6 (0.46) | ALDH1A1KDM4ERAB9AALOX5CYP1A2 | |
| SCHEMBL4275553 | 0.78 | ALOX5 (0.44) | BACE1ESR2HTTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010075544-A1 | NOVEL COLOR-FORMING COMPOUNDS AND USE THEREOF IN IMAGING MEMBERS AND METHODS | ZINK IMAGING, INC. (US) | 2010-07-01 | — | — | WO | disclosed |