Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.39 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3084672 | 0.86 | ALDH1A1 (0.40) | TGM2TYRALDH1A1KDM4ELMNA | |
| SCHEMBL28787492 | 0.81 | TGM2 (0.46) | TGM2TYRALDH1A1KDM4ELMNA | |
| SCHEMBL3080395 | 0.80 | ALDH1A1 (0.38) | TGM2ALDH1A1KDM4ELMNATDP1 | |
| SCHEMBL3097443 | 0.80 | ALDH1A1 (0.55) | ALDH1A1KDM4ELMNAKDM4A | |
| SCHEMBL3469954 | 0.80 | ATM (0.46) | TYRALDH1A1LMNATDP1 | |
| SCHEMBL3471108 | 0.79 | L3MBTL1 (0.53) | ALDH1A1LMNATDP1 | |
| SCHEMBL3093669 | 0.79 | TGM2 (0.44) | TGM2TYRALDH1A1KDM4ELMNA | |
| SCHEMBL3469893 | 0.78 | ALDH1A1 (0.48) | ALDH1A1KDM4ELMNATDP1 | |
| SCHEMBL17443354 | 0.77 | TGM2 (0.47) | TGM2TYRALDH1A1KDM4ELMNA | |
| SCHEMBL3096665 | 0.76 | ALDH1A1 (0.55) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2172450-B9 | NOVEL MALONIC ACID SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | MITSUBISHI TANABE PHARMA CORP (JP) | 2014-10-08 | — | — | EP | disclosed |
| EP-2172450-B1 | NOVEL MALONIC ACID SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | MITSUBISHI TANABE PHARMA CORP (JP) | 2013-10-16 | — | — | EP | disclosed |
| EP-2172450-A1 | NOVEL MALONIC ACID SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | Mitsubishi Tanabe Pharma Corporation (JP) | 2010-04-07 | — | — | EP | disclosed |