Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL524065 | 0.81 | LCK (0.43) | — | |
| Methane SCHEMBL27792691 | 0.79 | LCK (0.42) | — | |
| SCHEMBL3471004 | 0.74 | ALDH5A1 (0.39) | — | |
| SCHEMBL3019632 | 0.73 | BACE1 (0.50) | EGFR | |
| SCHEMBL19024853 | 0.73 | BACE1 (0.41) | EGFR | |
| SCHEMBL24445876 | 0.72 | CA12 (0.48) | — | |
| SCHEMBL8804437 | 0.72 | ALDH1A1 (0.48) | — | |
| Resorcinol SCHEMBL28044421 | 0.72 | CYP3A4 (0.50) | — | |
| Phenol SCHEMBL28239137 | 0.71 | CA12 (0.44) | — | |
| Catechol SCHEMBL28164265 | 0.71 | TTR (0.41) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100323969-A1 | Compounds Binding to P-Selectin | ASTELLAS PHARMA EUROPE B.V. (NL) | 2010-12-23 | — | — | US | disclosed |
| US-20090062186-A1 | Compounds Binding To P-Selectin | YAMANOUCHI ERUOPE B.V. (NL) | 2009-03-05 | — | — | US | disclosed |
| EP-1527086-B1 | COMPOUNDS BINDING TO P-SELECTIN | ASTELLAS PHARMA EUROP B V (NL) | 2008-01-09 | — | — | EP | disclosed |
| US-20060217294-A1 | Compounds binding to p-selectin | YAMANOUCHI EUROPE B.V. | 2006-09-28 | — | — | US | disclosed |
| EP-1527086-A1 | COMPOUNDS BINDING TO P-SELECTIN | YAMANOUCHI EUROPE B.V. (NL) | 2005-05-04 | — | — | EP | disclosed |
| WO-2004018502-A1 | COMPOUNDS BINDING TO P-SELECTIN | YAMANOUCHI EUROPE B.V. (NL) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062186-A1 | Compounds Binding To P-Selectin | SELP, SELPLG, SELL | EGFR 3499/4885 |
| US-20100323969-A1 | Compounds Binding to P-Selectin | SELP, SELPLG, SELL | EGFR 3499/4885 |
| US-20060217294-A1 | Compounds binding to p-selectin | SELP, SELPLG, SELL | EGFR 3499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.