Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | PITRM1 | Q5JRX3 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | GALR3 | O60755 | 1/20 | 0.52 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.52 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.51 |
| ▸ | ALPL | P05186 | 2/20 | 0.49 |
| ▸ | ALPG | P10696 | 2/20 | 0.49 |
| ▸ | ALPP | P05187 | 1/20 | 0.49 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TNF | P01375 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31441369 | 0.78 | MEN1 (0.71) | KMT2ARAB9AMEN1L3MBTL1GAA | |
| SCHEMBL28987743 | 0.78 | MEN1 (0.71) | KMT2ARAB9AMEN1L3MBTL1GAA | |
| SCHEMBL16756316 | 0.73 | TNF (0.51) | KMT2AMAPTTNFALDH1A1 | |
| SCHEMBL3964662 | 0.72 | MEN1 (0.53) | KMT2ARAB9AMEN1L3MBTL1GAA | |
| SCHEMBL9694564 | 0.72 | NOX4 (0.51) | KMT2ARAB9AMEN1L3MBTL1GAA | |
| SCHEMBL6231609 | 0.71 | KMT2A (0.51) | KMT2ARAB9AMEN1L3MBTL1GAA | |
| SCHEMBL7261471 | 0.71 | CYP1A2 (0.56) | KMT2ARAB9AMEN1GAAPITRM1 | |
| SCHEMBL7408535 | 0.70 | GALR3 (0.61) | KMT2ARAB9AL3MBTL1GSK3BNPC1 | |
| SCHEMBL7653998 | 0.70 | DCTPP1 (0.50) | KMT2ARAB9AMEN1L3MBTL1GAA | |
| SCHEMBL7970556 | 0.70 | GALR3 (1.00) | KMT2ARAB9AMEN1L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100317706-A1 | HNF4alpha MODULATORS AND METHODS OF USE | BUMHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317706-A1 | HNF4alpha MODULATORS AND METHODS OF USE | HNF4A, NCOA4, NR4A3 | KMT2A 1141/4885RAB9A 4607/4885MEN1 4481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.