Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | PITRM1 | Q5JRX3 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9804398 | 0.74 | NOX4 (0.37) | NOX4CTSBPITRM1MEN1KMT2A | |
| SCHEMBL3472014 | 0.72 | KMT2A (0.63) | NOX4CTSBPITRM1MEN1KMT2A | |
| SCHEMBL6675322 | 0.69 | KDM4E (0.59) | NOX4CTSBMEN1KMT2ARAB9A | |
| SCHEMBL9694885 | 0.68 | ALDH1A1 (0.39) | MEN1KMT2ARAB9AGAAL3MBTL1 | |
| SCHEMBL51277 | 0.67 | GPR35 (0.60) | NOX4CTSBMEN1KMT2AGAA | |
| SCHEMBL7544776 | 0.67 | MAPT (0.67) | MEN1KMT2ARAB9AGAAL3MBTL1 | |
| SCHEMBL14572673 | 0.67 | ALDH1A1 (0.38) | MEN1KMT2ARAB9AGAAL3MBTL1 | |
| SCHEMBL11780045 | 0.66 | L3MBTL1 (0.65) | MEN1KMT2AGAAL3MBTL1MAPT | |
| SCHEMBL4231830 | 0.66 | ALDH1A1 (0.58) | NOX4CTSBMEN1KMT2AGAA | |
| SCHEMBL216753 | 0.66 | GPR35 (0.58) | NOX4CTSBPITRM1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5169950-A | Reacting a 2-mercaptobenzothiazole, acarbonyl and a phenol; basic catalyst; polar solvent | CIBA-GEIGY CORPORATION (US) | 1992-12-08 | — | — | US | disclosed |
| US-5097039-A | Coating, lubricants | CIBA-GEIGY CORPORATION (US) | 1992-03-17 | — | — | US | disclosed |
| US-5069805-A | OIL ADDITIVES | CIBA-GEIGY CORPORATION (US) | 1991-12-03 | — | — | US | disclosed |
| EP-0259254-B1 | PHENOLIC BENZOTHIAZOLE DERIVATIVES AND THEIR USE AS CORROSION INHIBITORS | CIBA-GEIGY AG (CH) | 1991-04-17 | — | — | EP | disclosed |
| US-4894091-A | PROTECTIVE COATINGS, PHOTOSTABILIZERS, HEAT RESISTANCE | CIBA-GEIGY CORPORATION (US) | 1990-01-16 | — | — | US | disclosed |
| EP-0259254-A1 | Phenolic benzothiazole derivatives and their use as corrosion inhibitors | CIBA-GEIGY AG (CH) | 1988-03-09 | — | — | EP | disclosed |