SCHEMBL34722

SCHEMBL34722

C[CH]c1ccccc1[N+](=O)[O-]

nearest known ligand 0.55

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.55
NPSR1 Q6W5P4 1/20 0.54
HSD17B10 Q99714 1/20 0.54
XDH P47989 2/20 0.51
CA12 O43570 1/20 0.51
SOS1 Q07889 1/20 0.51
TDP1 Q9NUW8 2/20 0.50
CYP19A1 P11511 2/20 0.50
MAOB P27338 1/20 0.50
ALDH1A1 P00352 3/20 0.49
RAB9A P51151 1/20 0.49
ATM Q13315 1/20 0.49
ERN1 O75460 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL415690 0.83 MAPT (0.61) MAPTNPSR1HSD17B10SOS1CYP19A1
SCHEMBL7527194 0.83 MAPT (0.61) MAPTNPSR1HSD17B10SOS1CYP19A1
SCHEMBL7516374 0.83 MAPT (0.61) MAPTNPSR1HSD17B10SOS1CYP19A1
2-Nitrobenzaldehyde SCHEMBL3323403 0.83 ERN1 (0.59) MAPTNPSR1HSD17B10XDHCA12
SCHEMBL114440 0.82 MAPT (0.58) MAPTNPSR1HSD17B10XDHCA12
SCHEMBL14935499 0.82 MAPT (0.69) MAPTNPSR1CA12SOS1CYP19A1
SCHEMBL11049170 0.82 MAPT (0.69) MAPTNPSR1CA12SOS1CYP19A1
SCHEMBL9978289 0.82 MAPT (0.69) MAPTNPSR1CA12SOS1CYP19A1
SCHEMBL27861738 0.82 TDP1 (0.50) MAPTNPSR1HSD17B10XDHCA12
SCHEMBL27722602 0.80 TDP1 (0.48) MAPTNPSR1HSD17B10XDHCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1230 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4400166-A2 METHODS FOR IMPLANTING AND REVERSING STIMULI-RESPONSIVE IMPLANTS Contraline, Inc. (US) 2024-07-17 EP claimed
EP-3565484-B1 COMPOSITIONS FOR IMPLANTING AND REVERSING STIMULI-RESPONSIVE IMPLANTS CONTRALINE INC (US) 2024-04-03 EP claimed
US-11891668-B2 Methods for generating therapeutic delivery platforms THE UNIVERSITY OF KANSAS (US) 2024-02-06 US claimed
CN-116179554-A Conditional protein targeted degradation chimeric based on nucleic acid aptamer, and preparation method and application thereof 山东师范大学 2023-05-30 CN claimed
CN-115720626-A Method for locating individual molecules of a dye in a sample and method for generating a high resolution image of a structure in a sample 阿贝锐纳仪器有限公司 2023-02-28 CN claimed
EP-4025711-A2 ENHANCING SPECIFICITY OF ANALYTE BINDING 10X Genomics, Inc. (US) 2022-07-13 EP claimed
US-20210255074-A1 Degradable Microsphere and Use Thereof TSINGHUA UNIVERSITY (CN) 2021-08-19 US claimed
CN-109589307-B Preparation method of aptamer liposome 华南理工大学 2021-05-14 CN claimed
WO-2021083459-A1 PROCESS FOR THE SYNTHESIS OF DOPA COMPRISING A PHOTOLABILE PROTECTIVE GROUP, AND INTERMEDIATES FOR THE PREPARATION THEREOF CHIRACON GMBH (DE) 2021-05-06 WO claimed
EP-3808786-A1 DEGRADABLE MICROSPHERE AND USE THEREOF Tsinghua University (CN) 2021-04-21 EP claimed
WO-1997005155-A1 PHOTOLABILE 8-SUBSTITUTED CYCLIC NUCLEOTIDE ESTERS, METHODS OF PREPARING THEM AND THEIR USE FORSCHUNGSVERBUND BERLIN E.V. (DE) 1997-02-13 WO claimed
WO-1995029184-A1 POLYCATIONIC NUCLEIC BASES AND OLIGONUCLEOTIDES CONTAINING SAME UNIVERSITE LOUIS PASTEUR (FR) 1995-11-02 WO claimed
US-5389612-A Treating infections caused by clostridium histolyticum and pseudomonas aeruginosa; enzyme inhibitors COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1995-02-14 US claimed
US-5294618-A Psychological disorders MERCK SHARP & DOHME LIMITED (GB) 1994-03-15 US claimed
EP-0410535-A2 Octahydrobenzisoquinoline derivatives as antipsychotic agents MERCK SHARP & DOHME LTD. (GB) 1991-01-30 EP claimed
US-4556514-A INTERMEDIATES FOR PRODUCTION OF CARBAPENEM OR PENEM DERIVATIVES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-12-03 US claimed
US-4480096-A COLOR FORMERS FOR PRESSURE SENSITIVE OR HEAT SENSITIVE RECORDING CIBA-GEIGY CORPORATION (US) 1984-10-30 US claimed
EP-0106652-A1 Beta-lactam compounds and production thereof SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1984-04-25 EP claimed
US-4435003-A COLOR FORMERS IN PRESSURE AND/OR HEAT SENSITIVE RECORDING MATERIALS CIBA-GEIGY CORPORATION (US) 1984-03-06 US claimed
US-4254031-A Synthesis for the preparation of tetracyclic compounds AKZONA INCORPORATED (US) 1981-03-03 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210255074-A1 Degradable Microsphere and Use Thereof STUB1, PSMD14, ACP1 MAPT 1611/4885NPSR1 1980/4885HSD17B10 3836/4885
US-11891668-B2 Methods for generating therapeutic delivery platforms EXOSC4, EXOSC5, EXOSC9 MAPT 612/4885NPSR1 4498/4885HSD17B10 4466/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.