Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3858358 | 0.86 | NPSR1 (0.52) | PYCR1NPSR1MEN1KMT2AMAPT | |
| SCHEMBL3474780 | 0.82 | SIRT1 (0.42) | PYCR1NPSR1MEN1KMT2AMAPT | |
| SCHEMBL23189091 | 0.82 | NPY1R (0.41) | MTNR1APYCR1SLC6A4NPSR1NPY1R | |
| SCHEMBL7911472 | 0.82 | F13A1 (0.53) | NPSR1MAPTFFAR1 | |
| SCHEMBL4817531 | 0.81 | NPSR1 (0.63) | NPSR1MEN1KMT2AMAPTFFAR1 | |
| SCHEMBL20378745 | 0.80 | PYCR1 (0.42) | PYCR1SLC6A4NPSR1MEN1KMT2A | |
| SCHEMBL29086718 | 0.79 | LMNA (0.38) | PYCR1NPSR1MEN1KMT2AMAPT | |
| SCHEMBL1680569 | 0.78 | TYR (0.44) | PYCR1NPSR1NPY1RNPY2RMEN1 | |
| SCHEMBL10204025 | 0.78 | SETDB1 (0.43) | PYCR1MEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL9955740 | 0.78 | DGAT1 (0.46) | MTNR1AMPOSLC6A4TLR8DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010149360-A1 | PROCESS FOR THE PREPARATION OF BENZIMIDAZOLES | LONZA LTD (CH) | 2010-12-29 | — | — | WO | disclosed |