Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.51 |
| ▸ | ALOX5AP | P20292 | 15/20 | 0.50 |
| ▸ | FEN1 | P39748 | 15/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3468579 | 0.85 | GAA (0.48) | OPRM1OPRK1ALOX5APFEN1GAA | |
| SCHEMBL3471618 | 0.81 | ALOX5AP (0.49) | OPRM1OPRK1ALOX5APFEN1GAA | |
| SCHEMBL3467433 | 0.75 | KMT2A (0.49) | GAAMAPK1KMT2AMEN1POLB | |
| SCHEMBL3472577 | 0.72 | OPRM1 (0.38) | OPRM1OPRK1GAAMAPK1KMT2A | |
| SCHEMBL3469163 | 0.69 | CASP3 (0.55) | GAAMAPK1KMT2AMEN1POLB | |
| SCHEMBL13273663 | 0.68 | GAA (0.59) | GAAMAPK1KMT2AMEN1POLB | |
| SCHEMBL15916516 | 0.67 | ALOX5AP (1.00) | OPRM1OPRK1ALOX5APFEN1 | |
| SCHEMBL15916760 | 0.67 | ALOX5AP (1.00) | ALOX5APFEN1 | |
| SCHEMBL9098061 | 0.66 | KMT2A (0.61) | GAAMAPK1KMT2AMEN1POLB | |
| SCHEMBL2780829 | 0.65 | GAA (0.59) | GAAMAPK1KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077839-A1 | SUBSTITUTED OXINDOL CB2 AGONISTS FOR PAIN TREATMENT | WYETH LLC (FORMERLY KNOWN AS WYETH) (US) | 2010-07-08 | — | — | WO | disclosed |