Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ALOX5AP | P20292 | 8/20 | 0.48 |
| ▸ | FEN1 | P39748 | 8/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3471618 | 0.96 | ALOX5AP (0.49) | GAAMAPK1ALOX5APFEN1KMT2A | |
| SCHEMBL3472575 | 0.85 | OPRM1 (0.51) | GAAMAPK1ALOX5APFEN1KMT2A | |
| SCHEMBL3469163 | 0.74 | CASP3 (0.55) | GAAMAPK1KMT2AMEN1POLB | |
| SCHEMBL13273663 | 0.71 | GAA (0.59) | GAAMAPK1KMT2AMEN1POLB | |
| SCHEMBL9098061 | 0.70 | KMT2A (0.61) | GAAMAPK1KMT2AMEN1POLB | |
| SCHEMBL978033 | 0.69 | ALOX5AP (0.59) | GAAALOX5APFEN1KMT2AMEN1 | |
| SCHEMBL3468580 | 0.69 | CNR2 (0.47) | GAAKMT2AMEN1POLBKDM4E | |
| SCHEMBL2780829 | 0.69 | GAA (0.59) | GAAMAPK1KMT2AMEN1POLB | |
| SCHEMBL3522216 | 0.69 | PGR (0.63) | GAAMAPK1KMT2AMEN1POLB | |
| SCHEMBL3467433 | 0.68 | KMT2A (0.49) | GAAMAPK1KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077839-A1 | SUBSTITUTED OXINDOL CB2 AGONISTS FOR PAIN TREATMENT | WYETH LLC (FORMERLY KNOWN AS WYETH) (US) | 2010-07-08 | — | — | WO | claimed |