Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | CCR3 | P51677 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3474511 | 0.88 | CCR3 (0.48) | SIGMAR1HTR2AHTR2CHTR2BCHRM2 | |
| Hydrochloric Acid SCHEMBL3474349 | 0.82 | SIGMAR1 (0.52) | SIGMAR1HTR2AHTR2CHTR2BCHRM2 | |
| SCHEMBL10759530 | 0.76 | ACHE (0.62) | SIGMAR1HTR2AHTR2CHTR2BCHRM2 | |
| SCHEMBL5228406 | 0.75 | CCR3 (0.63) | SIGMAR1HTR2AHTR2CHTR2BACHE | |
| SCHEMBL18123522 | 0.75 | OPRM1 (0.65) | SIGMAR1CHRM2CHRM3OPRM1GAA | |
| SCHEMBL2499082 | 0.74 | OPRM1 (0.44) | SIGMAR1HTR2AHTR2CHTR2BCHRM2 | |
| SCHEMBL10762688 | 0.74 | KDM4E (0.57) | SIGMAR1OPRM1ACHECCR3CHRM4 | |
| SCHEMBL11689135 | 0.74 | ACHE (0.51) | SIGMAR1HTR2AHTR2CHTR2BACHE | |
| SCHEMBL16757422 | 0.74 | KMT2A (0.73) | CHRM2CHRM3OPRM1ACHECCR3 | |
| SCHEMBL11685098 | 0.73 | MEN1 (0.50) | SIGMAR1HTR2AHTR2CHTR2BACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100310477-A1 | Pharmaceutical compositions based on anticholingerics and additional active ingredients | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG. (DE) | 2010-12-09 | — | — | US | disclosed |
| US-7776315-B2 | Pharmaceutical compositions based on anticholinergics and additional active ingredients | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2010-08-17 | — | — | US | disclosed |
| US-20050148562-A1 | Pharmaceutical compositions based on anticholinergics and additional active ingredients | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2005-07-07 | — | — | US | disclosed |
| US-20040151770-A1 | Pharmaceutical compositions based on anticholinergics and NK1-receptor antagonists | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2004-08-05 | — | — | US | disclosed |
| US-6747044-B2 | ANTIINFLAMMATORY AGENTS; ANTIALLERGENS; ANTIULCER AGENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2004-06-08 | — | — | US | disclosed |
| US-6696042-B2 | INHALATION AEROSOL COMPRISING TIOTROPIUM SALT AND PROPELLANT GAS; RESPIRATORY SYSTEM DISORDERS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2004-02-24 | — | — | US | disclosed |
| EP-1370293-A2 | NOVEL MEDICAMENT COMPOSITIONS BASED ON ANTICHOLINERGICS AND ON NK1 RECEPTOR ANTAGONISTS | Boehringer Ingelheim Pharma GmbH & Co. KG (DE) | 2003-12-17 | — | — | EP | disclosed |
| US-20030212075-A1 | PHARMACEUTICAL COMPOSITIONS BASED ON ANTICHOLINERGICS AND NK1-RECEPTOR ANTAGONISTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2003-11-13 | — | — | US | disclosed |
| US-6620438-B2 | Arylglycinamide derivatives | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2003-09-16 | — | — | US | disclosed |
| EP-1328516-A1 | NOVEL NEUROKININ ANTAGONISTS, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID COMPOUNDS | Boehringer Ingelheim Pharma KG (DE) | 2003-07-23 | — | — | EP | disclosed |
| US-20020169181-A1 | Pharmaceutical compositions based on anticholinergics and NK1-receptor antagonists | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2002-11-14 | — | — | US | disclosed |
| US-20020147219-A1 | Neurokinin antagonists | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2002-10-10 | — | — | US | disclosed |
| WO-2002069944-A2 | NOVEL MEDICAMENT COMPOSITIONS BASED ON ANTICHOLINERGICS AND ON NK1 RECEPTOR ANTAGONISTS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2002-09-12 | — | — | WO | disclosed |
| WO-2002032865-A1 | NOVEL NEUROKININ ANTAGONISTS, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID COMPOUNDS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2002-04-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050148562-A1 | Pharmaceutical compositions based on anticholinergics and additional active ingredients | CHRM3, ADRA2C, PDE3A | SIGMAR1 992/4885HTR2A 630/4885HTR2C 306/4885 |
| US-20040151770-A1 | Pharmaceutical compositions based on anticholinergics and NK1-receptor antagonists | TACR2, CHRM3, TACR1 | SIGMAR1 303/4885HTR2A 506/4885HTR2C 542/4885 |
| US-20020147219-A1 | Neurokinin antagonists | TACR2, TACR1, TAC3 | SIGMAR1 168/4885HTR2A 91/4885HTR2C 54/4885 |
| US-20100310477-A1 | Pharmaceutical compositions based on anticholingerics and additional active ingredients | PDE4B, CHRM3, ADRA2C | SIGMAR1 946/4885HTR2A 810/4885HTR2C 402/4885 |
| US-20020169181-A1 | Pharmaceutical compositions based on anticholinergics and NK1-receptor antagonists | TACR2, CHRM3, TACR1 | SIGMAR1 303/4885HTR2A 506/4885HTR2C 542/4885 |
| US-20030212075-A1 | PHARMACEUTICAL COMPOSITIONS BASED ON ANTICHOLINERGICS AND NK1-RECEPTOR ANTAGONISTS | TACR2, CHRM3, TACR1 | SIGMAR1 303/4885HTR2A 506/4885HTR2C 542/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.