SCHEMBL3473012

SCHEMBL3473012

CCCCC(C(=O)O)P(=O)(O)S

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FDPS P14324 6/20 0.47
CA2 P00918 1/20 0.45
MAPK1 P28482 1/20 0.45
GPR84 Q9NQS5 3/20 0.39
FOLH1 Q04609 1/20 0.39
FFAR1 O14842 1/20 0.39
SLC1A3 P43003 1/20 0.39
SLC1A2 P43004 1/20 0.39
SLC1A1 P43005 1/20 0.39
MAPT P10636 1/20 0.38
LAP3 P28838 1/20 0.38
LCK P06239 1/20 0.38
PPARD Q03181 1/20 0.38
ZDHHC20 Q5W0Z9 1/20 0.38
ZDHHC2 Q9UIJ5 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2991458 0.83 FDPS (0.50) FDPSCA2MAPK1GPR84FOLH1
SCHEMBL3232568 0.83 FOLH1 (0.57) FDPSCA2MAPK1GPR84FOLH1
SCHEMBL3473016 0.82 CA2 (0.47) FDPSCA2MAPK1GPR84FOLH1
SCHEMBL3471393 0.79 FOLH1 (0.40) CA2MAPK1FOLH1LAP3
SCHEMBL389804 0.78 FDPS (0.57) FDPSGPR84FOLH1FFAR1MAPT
SCHEMBL2989636 0.78 CA2 (0.47) FDPSCA2MAPK1GPR84FFAR1
SCHEMBL3377184 0.76 FDPS (0.59) FDPSGPR84FOLH1FFAR1MAPT
SCHEMBL9841018 0.76 FDPS (0.59) FDPSGPR84FOLH1FFAR1MAPT
SCHEMBL3470937 0.76 FDPS (0.59) FDPSGPR84FOLH1FFAR1MAPT
SCHEMBL2023917 0.76 FDPS (0.59) FDPSGPR84FOLH1FFAR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2125029-B1 CONSTRUCTION AND USE OF TRANSFECTION ENHANCER ELEMENTS LIPOCALYX GMBH (DE) 2016-10-12 EP disclosed
US-20130011916-A1 CONSTRUCTION AND USE OF TRANSFECTION ENHANCER ELEMENTS LIPOCALYX GMBH (DE) 2013-01-10 US disclosed
US-20100022621-A1 CONSTRUCTION AND USE OF TRANSFECTION ENHANCER ELEMENTS MDRNA RESEARCH, INC. 2010-01-28 US disclosed
EP-0792275-B1 IMPROVED ANTIVIRAL PRODRUGS UNIV CALIFORNIA (US) 2004-03-03 EP disclosed
US-6002029-A Antiviral prodrugs CHIMERIX, INC. 1999-12-14 US disclosed
EP-0792275-A4 IMPROVED ANTIVIRAL PRODRUGS UNIV CALIFORNIA (US) 1998-02-25 EP disclosed
US-5696277-A CYTOMEGALOVIRUS, HERPES VIRUS Hostetler, Karl Y. (US) 1997-12-09 US disclosed
EP-0792275-A1 IMPROVED ANTIVIRAL PRODRUGS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1997-09-03 EP disclosed
WO-1996015132-A1 IMPROVED ANTIVIRAL PRODRUGS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1996-05-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100022621-A1 CONSTRUCTION AND USE OF TRANSFECTION ENHANCER ELEMENTS TEAD4, CREB1, ELF3 FDPS 3321/4885CA2 611/4885MAPK1 1640/4885
US-20130011916-A1 CONSTRUCTION AND USE OF TRANSFECTION ENHANCER ELEMENTS TEAD4, CREB1, ELF3 FDPS 3321/4885CA2 611/4885MAPK1 1640/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.