Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.66 |
| ▸ | LMNA | P02545 | 5/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | ATM | Q13315 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.66 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.66 |
| ▸ | SHBG | P04278 | 2/20 | 0.66 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.66 |
| ▸ | FYN | P06241 | 1/20 | 0.66 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.66 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.66 |
| ▸ | HTR2B | P41595 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | PGR | P06401 | 2/20 | 0.63 |
| ▸ | AR | P10275 | 2/20 | 0.63 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.63 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.63 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.63 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10360627 | 0.95 | ESR1 (0.73) | ESR1LMNASMN1; SMN2ATMKMT2A | |
| SCHEMBL8208515 | 0.93 | ESR1 (0.71) | ESR1LMNASMN1; SMN2ATMKMT2A | |
| SCHEMBL10361010 | 0.90 | SMN1; SMN2 (0.71) | ESR1LMNASMN1; SMN2ATMKMT2A | |
| SCHEMBL347436 | 0.89 | ESR1 (0.67) | ESR1LMNASMN1; SMN2ATMKMT2A | |
| SCHEMBL8177993 | 0.89 | ESR1 (0.65) | ESR1LMNASMN1; SMN2ATMKMT2A | |
| SCHEMBL8619796 | 0.87 | LMNA (0.69) | ESR1LMNASMN1; SMN2ATMKMT2A | |
| SCHEMBL8177995 | 0.86 | ESR1 (0.78) | ESR1LMNASMN1; SMN2ATMKMT2A | |
| SCHEMBL14360870 | 0.86 | ESR1 (0.78) | ESR1LMNASMN1; SMN2ATMKMT2A | |
| SCHEMBL3299315 | 0.85 | MAPT (0.81) | ESR1LMNASMN1; SMN2ATMKMT2A | |
| SCHEMBL5711620 | 0.85 | LMNA (0.68) | ESR1LMNASMN1; SMN2ATMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260014080-A1 | LIPOSOMAL PREPARATION WITH ENCAPSULATED HORMONES, METHOD OF PRODUCTION AND USE THEREOF | VAN BOGAERT GINA (BE) | 2026-01-15 | — | — | US | disclosed |
| WO-2023223235-A1 | LIPOSOMAL PREPARATION WITH ENCAPSULATED HORMONES, METHOD OF PRODUCTION AND USE THEREOF | PURNA PHARMACEUTICALS NV (BE) | 2023-11-23 | — | — | WO | disclosed |
| EP-1719768-B1 | NOVEL BENZOTHIAZEPINE AND BENZOTHIEPINE COMPOUNDS | ASAHI KASEI PHARMA CORP (JP) | 2012-04-25 | — | — | EP | disclosed |
| US-20120015925-A1 | NOVEL BENZOTHIAZEPINE AND BENZOTHIEPINE COMPOUNDS | ASAHI KASEI PHARMA CORPORATION (JP) | 2012-01-19 | — | — | US | disclosed |
| US-7973030-B2 | Benzothiazepine and benzothiepine compounds | ASAHI KASEI PHARMA CORPORATION (JP) | 2011-07-05 | — | — | US | disclosed |
| US-20100291242-A1 | ANTAGONIST AGAINST TOLERANCE TO ANTICANCER DRUGS | YOSHIKAZU SUGIMOTO (JP) | 2010-11-18 | — | — | US | disclosed |
| US-20080249036-A1 | Antagonist Against Tolerance to Anticancer Drugs | YOSHIKAZU SUGIMOTO (JP) | 2008-10-09 | — | — | US | disclosed |
| US-20070190041-A1 | Novel benzothiazepine and bensothiepine compounds | ASHAI KASEI PHARAMA CORPORATION (JP) | 2007-08-16 | — | — | US | disclosed |
| US-20070166362-A1 | Transdermal and transmucosal preparations | KABUSHIKI KAISHA SANGI (JP) | 2007-07-19 | — | — | US | disclosed |
| EP-1797900-A1 | PREPARATION FOR PERCUTANEOUS/PERMUCOSAL ABSORPTION | KABUSHIKI KAISHA SANGI (JP) | 2007-06-20 | — | — | EP | disclosed |
| EP-1785139-A1 | ANTAGONIST AGAINST TOLERANCE TO ANTICANCER DRUGS | JAPANESE FOUNDATION FOR CANCER RESEARCH (JP) | 2007-05-16 | — | — | EP | disclosed |
| EP-1719768-A1 | NOVEL BENZOTHIAZEPINE AND BENZOTHIEPINE COMPOUNDS | Asahi Kasei Pharma Corporation (JP) | 2006-11-08 | — | — | EP | disclosed |
| US-6444420-B2 | NERVOUS SYSTEM DISORDERS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2002-09-03 | — | — | US | disclosed |
| US-20010016325-A1 | Activation of novel estrogen receptor supports and neuronal viability and function | BOARD OF TRUSTEE OF THE LELAND STANFORD JUNIOR UNIVERSITY, THE | 2001-08-23 | — | — | US | disclosed |
| US-6265147-B1 | DETECTING MODULATORS OF BRAIN ACTIVITY; MIX MODULATOR WITH RECEPTORS AND DETECT ACTIVATION OF RECEPTORS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2001-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260014080-A1 | LIPOSOMAL PREPARATION WITH ENCAPSULATED HORMONES, METHOD OF PRODUCTION AND USE THEREOF | NR5A1, SHBG, GNRHR | ESR1 188/4885LMNA 796/4885SMN1; SMN2 2999/4885 |
| US-20010016325-A1 | Activation of novel estrogen receptor supports and neuronal viability and function | ESR1, GPER1, ESR2 | ESR1 1/4885LMNA 3505/4885SMN1; SMN2 166/4885 |
| US-20120015925-A1 | NOVEL BENZOTHIAZEPINE AND BENZOTHIEPINE COMPOUNDS | SLC10A1, SREBF1, SPTLC1 | ESR1 1904/4885LMNA 1909/4885SMN1; SMN2 4162/4885 |
| US-20070190041-A1 | Novel benzothiazepine and bensothiepine compounds | SLC10A1, GOT1, CES1 | ESR1 2170/4885LMNA 2785/4885SMN1; SMN2 4351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.