SCHEMBL3474355

SCHEMBL3474355

CCCCCCCCc1ccc(-c2c3nc(c(-c4ccc(CCCCCCCC)cc4)c4ccc([nH]4)c(-c4ccc(CCCCCCCC)cc4)c4nc(c(-c5ccc(CCCCCCCC)cc5)c5ccc2[nH]5)C=C4)C=C3)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TERT O14746 3/20 0.51
TOP1 P11387 4/20 0.48
CYCS P99999 3/20 0.47
ENPP2 Q13822 1/20 0.46
HSD17B10 Q99714 3/20 0.43
KDM4E B2RXH2 2/20 0.43
ALDH1A1 P00352 2/20 0.43
MEN1 O00255 1/20 0.43
USP2 O75604 1/20 0.43
GAA P10253 1/20 0.43
MAPT P10636 1/20 0.43
HPGD P15428 1/20 0.43
RAB9A P51151 1/20 0.43
KMT2A Q03164 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
TSHR P16473 1/20 0.43
ABCG2 Q9UNQ0 1/20 0.43
ESR1 P03372 2/20 0.42
ADRA2A P08913 2/20 0.42
ADORA3 P0DMS8 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10717959 1.00 TERT (0.51) TERTTOP1CYCSENPP2HSD17B10
SCHEMBL7738094 1.00 TERT (0.51) TERTTOP1CYCSENPP2HSD17B10
SCHEMBL7164187 0.94 TERT (0.54) TERTTOP1CYCSENPP2RAB9A
SCHEMBL708666 0.88 TERT (0.48) TERTTOP1CYCSENPP2RAB9A
SCHEMBL706881 0.87 TERT (0.47) TERTTOP1CYCSENPP2RAB9A
SCHEMBL17904262 0.86 TERT (0.40) TERTTOP1CYCSENPP2HSD17B10
Bicarbonate SCHEMBL10724119 0.85 ENPP2 (0.63) TERTTOP1CYCSENPP2ALDH1A1
SCHEMBL17904261 0.83 TERT (0.44) TERTTOP1CYCSENPP2ABCG2
SCHEMBL17904263 0.83 TERT (0.44) TERTTOP1CYCSENPP2RAB9A
SCHEMBL12893301 0.83 TERT (0.44) TERTTOP1CYCSENPP2ABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010088723-A1 DYE COMPOSITION FOR USE IN PHOTOELECTRIC MATERIAL UNIVERSITY OF WOLLONGONG (AU) 2010-08-12 WO disclosed
US-20080283122-A1 Beta-Substituted Porphyrins CAMPBELL WAYNE MASON 2008-11-20 US disclosed
WO-2006038823-A1 BETA-SUBSTITUTED PORPHYRINS MASSEY UNIVERSITY (NZ) 2006-04-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080283122-A1 Beta-Substituted Porphyrins PPOX, HMBS, CRY1 TERT 505/4885TOP1 2190/4885CYCS 225/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.