SCHEMBL3474987

SCHEMBL3474987

O=S(=O)(O)c1ccc(O)nc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.61
LMNA P02545 2/20 0.50
NAPRT Q6XQN6 1/20 0.47
ALDH1A1 P00352 6/20 0.43
TSHR P16473 3/20 0.43
NT5E P21589 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.41
HSD17B10 Q99714 3/20 0.41
TDP1 Q9NUW8 4/20 0.39
HPGD P15428 2/20 0.37
POLB P06746 2/20 0.36
CYP2D6 P10635 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
MAPT P10636 1/20 0.36
HTT P42858 1/20 0.36
GLO1 Q04760 1/20 0.36
GAA P10253 2/20 0.35
NSD2 O96028 1/20 0.35
PLCG1 P19174 1/20 0.35
DNMT1 P26358 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30017884 1.00 KDM4E (0.61) KDM4ELMNANAPRTALDH1A1TSHR
SCHEMBL8438731 0.81 KDM4E (0.65) KDM4ELMNANAPRTALDH1A1TSHR
SCHEMBL29412604 0.80 KDM4E (0.39) KDM4ELMNASMN1; SMN2MAPTGAA
SCHEMBL29191928 0.80 ALDH1A1 (0.44) KDM4ELMNAALDH1A1TSHRSMN1; SMN2
SCHEMBL1642998 0.80 ENPP2 (0.52) KDM4EENPP2
SCHEMBL9239536 0.79 KDM4E (0.63) KDM4ELMNANAPRTALDH1A1TSHR
SCHEMBL8847357 0.77 KDM4E (0.61) KDM4ELMNANAPRTALDH1A1TSHR
SCHEMBL2175053 0.77 GAA (0.44) KDM4ELMNASMN1; SMN2TDP1CYP2D6
SCHEMBL4804922 0.76 KDM4E (0.59) KDM4ELMNANAPRTALDH1A1SMN1; SMN2
SCHEMBL1700622 0.76 KDM4E (1.00) KDM4ELMNANAPRTALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170088800-A1 DETERGENT COMPOSITIONS CONTAINING PYRIDINOL-N-OXIDE COMPOSITIONS PROCTER & GAMBLE (US) 2017-03-30 US claimed
EP-2744881-B1 DETERGENT COMPOSITIONS CONTAINING PYRIDINOL-N-OXIDE COMPOUNDS PROCTER & GAMBLE (US) 2016-01-20 EP claimed
US-8841247-B2 Detergent compositions containing pyridinol-N-oxide compositions THE PROCTER & GAMBLE COMPANY (US) 2014-09-23 US claimed
EP-2744881-A1 DETERGENT COMPOSITIONS CONTAINING PYRIDINOL-N-OXIDE COMPOUNDS The Procter and Gamble Company (US) 2014-06-25 EP claimed
WO-2013025742-A1 DETERGENT COMPOSITIONS CONTAINING PYRIDINOL-N-OXIDE COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 2013-02-21 WO claimed
US-20130045910-A1 DETERGENT COMPOSITIONS CONTAINING PYRIDINOL-N-OXIDE COMPOSITIONS THE PROCTER & GAMBLE COMPANY 2013-02-21 US claimed
JP-4304893-A None JP disclosed
US-12036301-B2 Deodorant and antiperspirant compositions THE PROCTER & GAMBLE COMPANY (US) 2024-07-16 US disclosed
EP-4386035-A1 POLYALKYLENE-OXIDE-CONTAINING COMPOUND Nippon Shokubai Co., Ltd. (JP) 2024-06-19 EP disclosed
CN-113873989-B Synergistic anti-inflammatory compositions 宝洁公司 2024-05-28 CN disclosed
US-11980612-B2 Synergistic anti-inflammatory compositions THE PROCTER & GAMBLE COMPANY (US) 2024-05-14 US disclosed
CN-113873986-B Improving stability of zinc pyrithione in oxidizing environments such as scalp sebum fluids 宝洁公司 2024-04-26 CN disclosed
EP-4352192-A1 TRANSPARENT SOAP BAR The Procter & Gamble Company (US) 2024-04-17 EP disclosed
EP-0603557-B1 Catalyst compositions and catalytic processes PHILLIPS PETROLEUM CO (US) 1997-07-30 EP disclosed
US-5461126-A Process of polymerizing olefins using organonickel catalyst compositions PHILLIPS PETROLEUM COMPANY (US) 1995-10-24 US disclosed
US-5424165-A Printing durability, storage stability FUJI PHOTO FILM CO., LTD. (JP) 1995-06-13 US disclosed
US-5332708-A Ethylene polymerization catalyst, organonickel compound and a heterocyclic nitrogen compound PHILLIPS PETROLEUM COMPANY (US) 1994-07-26 US disclosed
EP-0603557-A1 Catalyst compositions and catalytic processes PHILLIPS PETROLEUM COMPANY (US) 1994-06-29 EP disclosed
EP-0547578-A1 Light-sensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1993-06-23 EP disclosed
JP-H04304893-A PRODUCTION OF HYDROXIDE OF NITROGEN-CONTAINING HETEROCYCLIC COMPOUND BY MICROORGANISM IKEDA SHIYOKUKEN KK 1992-10-28 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12036301-B2 Deodorant and antiperspirant compositions LPO, TH, PON1 KDM4E 2449/4885LMNA 2614/4885NAPRT 442/4885
US-11980612-B2 Synergistic anti-inflammatory compositions IL1B, IL6, TNF KDM4E 4664/4885LMNA 2406/4885NAPRT 703/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.